Study Physician: CAR-T MS Immunotherapy Lead

AstraZeneca plc; Cambridge (MA); Vor Ort; USD 250.000 - 375.000; Vollzeit

Benefits dieser Stelle

Incentives program

Equity-based awards

Retirement programs

Health, dental, and vision coverage

Zusammenfassung

AstraZeneca plc in Cambridge, MA is seeking a neurologist to lead a first-of-its-kind CAR-T study in multiple sclerosis. You will serve as the study-level medical authority for a global, multi-cohort program, shaping how immune therapies are delivered and assessed.

Based at Kendall Square, you will partner with clinical scientists and cross-functional teams to ensure patient safety, drive data-led progress, and guide dose escalation and regulatory documentation.

Qualifikationen

• MD or equivalent with board certification in neurology and substantial MS experience.
• Clinical research experience including design or delivery of clinical studies.
• Knowledge of MS trial methodology, endpoints, biostatistics, and FDA/EMA/ICH GCP requirements.
• Ability to influence across a matrix and communicate complex decisions clearly.

Aufgaben

• Own the medical design, delivery and interpretation of a multi-cohort CAR-T study in MS, ensuring integrity and compliant progress.
• Lead medical monitoring from eligibility to long-term follow-up, ensuring patient safety and consistency across global sites.
• Adjudicate MS events and support regulatory documentation and disclosures.

Kenntnisse

Neurology

MS expertise

Clinical research

GCP knowledge

Ausbildung

MD or equivalent (Neurology board)

Jobbeschreibung

AstraZeneca plc in Cambridge, MA is seeking a neurologist to lead a first-of-its-kind CAR-T study in multiple sclerosis. You will serve as the study-level medical authority for a global, multi-cohort program, shaping how immune therapies are delivered and assessed.

Based at Kendall Square, you will partner with clinical scientists and cross-functional teams to ensure patient safety, drive data-led progress, and guide dose escalation and regulatory documentation.