Structural Biologist III

Ambry Genetics Corporation; Aliso Viejo (CA); On-site; USD 120,000 - 170,000; Full time

Benefits offered by this job

Medical coverage

Dental coverage

Vision coverage

FSA

Paid sick leave

Generous PTO

401k program

Job summary

Ambry Genetics Corporation is seeking a Structural Biologist III in Aliso Viejo, California, to drive biomolecular structure-based insights across biology, bioinformatics, software engineering, and clinical teams.

You will design tools and methods for structure-guided clinical decision support, lead the structural biology group, and mentor junior staff while ensuring timely project delivery and high-quality documentation.

Qualifications

• PhD in computational biology, structural biology, biophysics, bioinformatics, or equivalent.
• Minimum 5 years of R&D experience in computational structural biology or related fields, including at least 2 years post-doctoral or industrial experience and 2 years management experience.

Responsibilities

• Provide structural biology support for variant analyses through structure-function interpretation.
• Develop methods and tools for structural modeling, molecular dynamics, and clinical variant assessment.
• Coordinate cross-functional efforts across Bioinformatics, R&D, and reporting teams for clinical projects.

Skills

Python

R

C/C++

Java

SQL

Molecular dynamics

Education

PhD in computational/structural biology or biophysics

Tools

Bioinformatics software

Molecular dynamics software

Job description

Structural Biologist III page is loaded## Structural Biologist IIIlocations: Ambry Headquarterstime type: Full timeposted on: Posted 10 Days Agojob requisition id: JR202600911**Compensation:**$120,000 - $170,000**Role Overview**The Structural Biologist III collaborates across biology, bioinformatics, software engineering, and clinical teams to design tools and methodologies leveraging biomolecular structural data to guide clinical decisions.**Key Responsibilities*** Provide structural biology support for variant analyses through structure-function relationship interpretation.* Develop novel methods, protocols, and tools for structural modeling, molecular dynamics, and clinical variant assessment on internal platforms.* Partner with statisticians and data scientists to validate algorithms and data collection workflows.* Coordinate cross-functional efforts across Bioinformatics, R&D, and reporting teams for clinical research projects.* Write testable, production-grade code adhering to SDLC standards and code review best practices.* Maintain technical documentation, SOPs, and knowledge bases while mentoring junior staff.* Direct and lead the structural team through both soft and explicit leadership ensuring timely project completion* Support, inform, and educate leadership and stakeholders about project progress and blockers.**Qualifications & Competencies*** Education: PhD in computational biology, structural biology, biophysics, bioinformatics, or equivalent.* Experience: Minimum 5 years of R&D experience in computational structural biology or related fields, including at least 2 years of post-doctoral or industrial experience and 2 years management experience.* Technical Skills: Fluency/proficiency in scripting/languages (Python, R, Perl, C/C++, Java, SQL) and bioinformatics/modeling software. Strong background in systems biology, molecular dynamics, and experimental techniques (X-ray, Cryo-EM).**PRIVACY NOTICES**To review Ambry's Privacy Notice, Click here:To review the California privacy notice, click here:To review the UKG privacy notice, click here:**Equal Opportunity Employer**This employer is required to notify all applicants of their rights pursuant to federal employment laws. For further information, please review the notice from the Department of Labor.Ambry Genetics Corporation is a CAP-accredited and CLIA-licensed molecular genetics laboratory based in Aliso Viejo, California. We are a genetics-based healthcare company that is dedicated to open scientific exchange so we can work together to understand and treat all human disease faster.At Ambry, everyone is welcome. A career at Ambry Genetics is a chance to be part of a dynamic company that aims to improve health by understanding the relationships between genetics and human disease. We earned our reputation as industry leaders by responsibly introducing cutting-edge genetic testing solutions and continually sharing what we learn with the global scientific community.At Ambry you will be learning, challenging yourself, and having fun while collaborating with teammates through the open exchange of ideas. Our outstanding benefits program includes medical, dental, vision, FSA, paid sick leave and generous paid time off (PTO) program. The Company reserves the right to make changes to the 401k plan from time to time. You can learn more about the benefits here. Ambry Genetics is an Equal Opportunity Employer (EOE) and we maintain a drug-free work environment.The Company believes in second chance employment. Qualified applicants with arrest or conviction history will be considered regardless of their arrest or conviction history, consistent with local laws such as Los Angeles County Fair Chance Ordinance and the California Fair Chance Act. You do not need to disclose your criminal history or participate in a background check until a conditional job offer is made to you. After making a conditional offer and running a background check, if the Company is concerned about conviction that is directly related to the job, you will be given the chance to explain the circumstances surrounding the conviction, provide mitigating evidence, or challenge the accuracy of the background report. For the purpose of the above job description, \"Essential Functions\" are \"Material Job Duties\".Our salary ranges are determined by role, level, and location. The range displayed on each job posting reflects the minimum and maximum target for new hire salaries for the position across all US locations. Within the range, individual pay is determined by work location and additional factors, including job-related skills, experience, and relevant education or training.All qualified applicants will receive consideration for employment without regard to race (and traits historically associated with race, including, but not limited to hair texture and protective hairstyles such as braids, locks, and twists), color, creed, religion, sex, sexual orientation, gender identity, gender expression (including transgender status), national origin, ancestry, age, marital status or protected veteran status and will not be discriminated against on the basis of disability, protected medical condition as defined by applicable state or local law, genetic information, or any other characteristic protected by applicable federal, state, or local laws and ordinances. If you have a disability or special need that requires accommodation, please contact us at [e-mail] does not accept unsolicited resumes from individual recruiters, third party recruiting agencies, outside recruiters or firms without an executed contract in place. We are not responsible for any fees related to resumes that are unsolicited or are received by Ambry. Such resumes will be deemed the sole property of Ambry and will be processed accordingly.