Staff Scientist - Membrane Protein Design & Cryo-EM

Scripps Research; San Diego (CA); On-site; USD 78,000 - 109,000; Full time

Benefits offered by this job

Retirement plan

Health and welfare plans

Flexible spending accounts

Paid vacation

On-site parking

Job summary

Scripps Research in La Jolla, CA, seeks a Staff Scientist to lead projects in chemical and structural biology, focusing on membrane proteins, protein design and biophysical characterization. You'll guide research with collaborators, train staff, and drive translational opportunities through advanced assays.

The role emphasizes cell biology, biochemistry, and structural biology (cryo-EM) with opportunities to expand molecular design and AI-assisted approaches in a collaborative environment.

Qualifications

• Ph.D. in an appropriate scientific discipline required.
• Minimum of 2 years postdoctoral experience.
• Strong track record of research productivity (publications/patents).
• Able to collaborate and communicate with colleagues and management.

Responsibilities

• Design, execute, analyze and troubleshoot experiments in cell biology and membrane protein biochemistry.
• Maintain reports and present results to leadership.
• Train and mentor junior lab members in protocols.
• Collaborate with internal/external teams and coordinate with collaborators.
• Develop robust recombinant protein expression and purification workflows.
• Characterize biophysical properties and interactions of synthetic proteins.
• Execute protein-protein interaction and signaling assays in mammalian cells.

Skills

Protein production

Membrane proteins

Cryo-EM

Mammalian cell culture

Plasmid cloning

Protein biophysics

Cell signaling assays

Protein engineering

Education

PhD in science

Tools

Cryo-EM

Plasmid cloning

Co-immunoprecipitation

Job description

Scripps Research in La Jolla, CA, seeks a Staff Scientist to lead projects in chemical and structural biology, focusing on membrane proteins, protein design and biophysical characterization. You'll guide research with collaborators, train staff, and drive translational opportunities through advanced assays.

The role emphasizes cell biology, biochemistry, and structural biology (cryo-EM) with opportunities to expand molecular design and AI-assisted approaches in a collaborative environment.