Sr Assoc Scientist, Bioconjugate Analytics (ABMS)

Regeneron Pharmaceuticals, Inc.; Village of Tarrytown (NY); On-site; USD 95,000 - 135,000; Full time

Benefits offered by this job

Student Loan Paydown program & Tuition

Family Care Benefits

Relocation Assistance

Inclusion, Culture and Well‑Being

Job summary

Regeneron Pharmaceuticals, Inc. in Tarrytown, NY is seeking a Sr. Associate Scientist to join the Bioconjugate Analytics (BCA) team within the ABMS Group.

You will develop LC-MS-based analytical methods to advance the bioconjugate pipeline, including ADCs, AOCs, ATLs, and other modalities. You will perform sample prep, LC-MS experiments, data analysis, and contribute to process development, regulatory submissions, and scientific problem-solving while collaborating with cross-functional teams to

Qualifications

• Master's degree with at least 3 years of relevant experience or Bachelor's degree with at least 6 years of relevant experience in Chemistry, Biochemistry, Analytical Chemistry, Pharmaceutical Sciences, or related field
• Industrial or academic experience in analytical characterization of protein therapeutics, bioconjugates, or other therapeutic modalities
• Strong knowledge of and hands-on experience with LC-MS-based characterization of proteins, peptides, and bioconjugates (e.g., ADCs, AOCs, ATLs) including sample prep, LC, MS, and data analysis
• Enjoyment of developing and troubleshooting analytical methods and solving complex scientific and technical problems

Responsibilities

• Develop and apply LC-MS-based analytical methods to characterize bioconjugates and other therapeutic protein candidates across R&D programs
• Perform sample preparation, LC-MS experiments, and data analysis using relevant software and bioinformatics tools to characterize product quality attributes; document results in ELN entries, presentations, and reports
• Support process development, R&D activities, and regulatory submissions through analytical characterization and scientific problem-solving
• Collaborate with cross-functional teams to understand analytical needs, coordinate samples and study activities, and align priorities, timelines, and deliverables
• Interpret and communicate scientific results through project and group meetings, technical reports, regulatory documents, internal and external conferences, and peer-reviewed publications

Skills

LC-MS characterization

Data analysis

Cross-functional collaboration

Analytical method development

Problem solving

Education

Master's degree

Bachelor's degree

Tools

Orbitrap

Q-TOF

Triple quadrupole

Protein Metrics

ChemDraw

Skyline

Proteome Discoverer

Compound Discoverer

Job description

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a highly motivated Sr. Associate Scientist to join the Bioconjugate Analytics (BCA) team within the Analytical and Biological Mass Spectrometry (ABMS) Group. In this role, you will develop and apply LC-MS-based analytical methods to advance Regeneron's bioconjugate pipeline across all stages of development, including antibody-drug conjugates (ADCs), antibody-oligonucleotide conjugates (AOCs), antibody-tethered ligands (ATLs), and other emerging bioconjugate modalities. You will apply state-of-the‑art mass spectrometry and analytical technologies to characterize bioconjugates and other therapeutic protein candidates, with a focus on critical quality attributes and process development, while collaborating closely with cross‑functional teams to coordinate samples, study activities, priorities, and timelines.

This position offers the opportunity to contribute to a fast‑growing, science‑driven organization making a meaningful difference to patients worldwide.

When & where:

• Shift Requirements: Full-time
• Location: On-site in Tarrytown, NY

What you'll do:

• Develop and apply LC-MS-based analytical methods to characterize bioconjugates and other therapeutic protein candidates across R&D programs
• Perform sample preparation, LC-MS experiments, and data analysis using relevant software and bioinformatics tools to characterize product quality attributes; document results in electronic laboratory notebook (ELN) entries, presentations, and reports
• Support process development, R&D activities, and regulatory submissions through analytical characterization and scientific problem-solving
• Collaborate with cross‑functional teams to understand analytical needs, coordinate samples and study activities, and align priorities, timelines, and deliverables
• Interpret and communicate scientific results through project and group meetings, technical reports, regulatory documents, internal and external conferences, and peer‑reviewed publications

Must-haves:

• Master's degree with at least 3 years of relevant experience, or a Bachelor's degree with at least 6 years of relevant experience, in Chemistry, Biochemistry, Analytical Chemistry, Pharmaceutical Sciences, or a related field
• Industrial or academic experience in analytical characterization of protein therapeutics, bioconjugates, or other therapeutic modalities
• Strong knowledge of and hands‑on experience with LC-MS-based characterization of proteins, peptides, and bioconjugates (e.g., ADCs, AOCs, and ATLs), including sample preparation, liquid chromatography, mass spectrometry, and data analysis
• Enjoyment of developing and troubleshooting analytical methods and solving complex scientific and technical problems

Preferred / nice‑to‑haves:

• Experience with advanced mass spectrometer platforms (e.g., Orbitrap, Q‑TOF, and triple quadrupole), liquid chromatography, and relevant data processing software (e.g., Protein Metrics, ChemDraw, Skyline, Proteome Discoverer, Compound Discoverer, and other related analytical tools)

Benefits:

• Student Loan Paydown program & Tuition Reimbursement
• Family Care Benefits
• Relocation Assistance
• Inclusion, Culture and Well‑Being programs (including physical & mental health)

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role l