Sr Assoc Scientist, Bioconjugate Analytics (ABMS)

BioSpace; Village of Tarrytown (NY); On-site; USD 80,000 - 131,000; Full time

Benefits offered by this job

Student Loan Paydown

Tuition Reimbursement

Family Care Benefits

Relocation Assistance

Well-Being Programs

Job summary

Regeneron is seeking a Sr. Associate Scientist to join the Bioconjugate Analytics team in the ABMS Group. You will develop and apply LC-MS-based analytical methods to characterize bioconjugates and other therapeutic proteins across R&D stages, including ADCs, AOCs, and ATLs.

You will advance the bioconjugate pipeline and focus on critical quality attributes, working closely with cross-functional teams. This role offers opportunities to contribute to fast-paced, science-driven programs and to

Qualifications

• Master's degree with 3+ years of relevant experience or Bachelor's degree with 6+ years in Chemistry/ Biochemistry/ Analytical Chemistry
• Industrial or academic experience in analytical characterization of protein therapeutics/bioconjugates
• Strong LC-MS-based characterization of proteins, peptides, and bioconjugates including sample prep, LC, MS, and data analysis
• Enjoy developing and troubleshooting analytical methods and solving complex scientific problems

Responsibilities

• Develop and apply LC-MS-based analytical methods to characterize bioconjugates across R&D programs
• Perform sample prep, LC-MS experiments, and data analysis; document results in ELN and reports
• Support process development, R&D activities, and regulatory submissions through analytical characterization
• Collaborate with cross-functional teams to coordinate samples, activities, and timelines
• Communicate results through project meetings, reports, and publications

Skills

LC-MS Analysis

Bioconjugates

Protein Therapeutics

Data Analysis

ELN Documentation

Education

Master's degree in Chemistry

Bachelor's degree in Chemistry

Tools

Orbitrap

Q-TOF

Triple Quadrupole

Protein Metrics

Skyline

Proteome Discoverer

Compound Discoverer

Job description

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a highly motivated Sr. Associate Scientist to join the Bioconjugate Analytics (BCA) team within the Analytical and Biological Mass Spectrometry (ABMS) Group. In this role, you will develop and apply LC-MS-based analytical methods to advance Regenerons bioconjugate pipeline across all stages of development, including antibody-drug conjugates (ADCs), antibody-oligonucleotide conjugates (AOCs), antibody-tethered ligands (ATLs), and other emerging bioconjugate modalities. You will apply state-of-the-art mass spectrometry and analytical technologies to characterize bioconjugates and other therapeutic protein candidates, with a focus on critical quality attributes and process development, while collaborating closely with cross-functional teams to coordinate samples, study activities, priorities, and timelines.

This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

When & Where

Shift Requirements: Full-time

Location: On-site in Tarrytown, NY

What Youll Do

• Develop and apply LC-MS-based analytical methods to characterize bioconjugates and other therapeutic protein candidates across R&D programs
• Perform sample preparation, LC-MS experiments, and data analysis using relevant software and bioinformatics tools to characterize product quality attributes; document results in electronic laboratory notebook (ELN) entries, presentations, and reports
• Support process development, R&D activities, and regulatory submissions through analytical characterization and scientific problem-solving
• Collaborate with cross-functional teams to understand analytical needs, coordinate samples and study activities, and align priorities, timelines, and deliverables
• Interpret and communicate scientific results through project and group meetings, technical reports, regulatory documents, internal and external conferences, and peer-reviewed publications

The Environment And Physical Rhythms Of This Role

This is an innovative, fast-paced, and collaborative R&D laboratory environment requiring results-driven, highly organized, and adaptable scientific curiosity, with the ability to learn new technologies.

Strong cross-functional collaboration and communication, with the ability to build productive working relationships and coordinate samples, activities, priorities, timelines, and deliverables across multiple programs, is required.

Must-haves

Lets find out if were a fit:

• Masters degree with at least 3 years of relevant experience, or a Bachelors degree with at least 6 years of relevant experience, in Chemistry, Biochemistry, Analytical Chemistry, Pharmaceutical Sciences, or a related field
• Industrial or academic experience in analytical characterization of protein therapeutics, bioconjugates, or other therapeutic modalities
• Strong knowledge of and hands-on experience with LC-MS-based characterization of proteins, peptides, and bioconjugates (e.g., ADCs, AOCs, and ATLs), including sample preparation, liquid chromatography, mass spectrometry, and data analysis
• Enjoyment of developing and troubleshooting analytical methods and solving complex scientific and technical problems

Preferred / Nice-to-haves

• Experience with advanced mass spectrometer platforms (e.g., Orbitrap, Q-TOF, and triple quadrupole), liquid chromatography, and relevant data processing software (e.g., Protein Metrics, ChemDraw, Skyline, Proteome Discoverer, Compound Discoverer, and other related analytical tools)

Thrive today. Grow tomorrow.

Benefits

• Student Loan Paydown program & Tuition Reimbursement
• Family Care Benefits
• Relocation Assistance
• Inclusion, Culture and Well-Being programs (including physical & mental health)

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process.

Salary Range (annually)

$80,300.00 - $131,100.00