Sr Assoc Scientist, Bioconjugate Analytics (ABMS)

Regeneron Pharmaceuticals, Inc (USA); Village of Tarrytown (NY); On-site; USD 80,000 - 131,000; Full time

Benefits offered by this job

Student Loan Paydown program

Tuition Reimbursement

Relocation Assistance

Inclusion, Culture and Well-Being

Job summary

Regeneron Pharmaceuticals, Inc. in Tarrytown, NY seeks a Sr. Associate Scientist to join the Bioconjugate Analytics team.

You will develop LC-MS methods to characterize bioconjugates and therapeutic proteins, collaborate across functions, and contribute to regulatory submissions. On-site work in Tarrytown is required. The role requires a Master’s with 3+ years or Bachelor's with 6+ years in Chemistry-related fields, with hands-on LC-MS experience and problem-solving skills.

Qualifications

• Master's degree with at least 3 years of relevant experience or Bachelor's with at least 6 years in Chemistry/Biochemistry/Analytical Chemistry or related field.
• Industrial or academic experience in analytical characterization of protein therapeutics, bioconjugates, or related modalities.
• Strong LC-MS-based characterization of proteins, peptides, and bioconjugates including sample prep, LC, MS and data analysis.
• Enjoyment of developing and troubleshooting analytical methods and solving complex scientific problems.

Responsibilities

• Develop and apply LC-MS-based analytical methods to characterize bioconjugates and therapeutic proteins across R&D programs.
• Perform sample preparation, LC-MS experiments, and data analysis; document results in ELN, reports, and presentations.
• Support process development, R&D activities, and regulatory submissions through analytical characterization and problem-solving.
• Collaborate with cross-functional teams to coordinate samples, study activities, and timelines.
• Communicate results through meetings, technical reports, regulatory documents, and conferences.

Skills

LC-MS-based characterization

Analytical problem-solving

Data analysis

Cross-functional collaboration

Education

Master's degree in Chemistry/Biochemistry/Analytical Chemistry/Pharmaceutical Sciences or related field

Bachelor's degree in Chemistry/Biochemistry/Analytical Chemistry/Pharmaceutical Sciences or related field with 6+ years experience

Tools

Orbitrap

Q-TOF

Triple quadrupole

Protein Metrics

ChemDraw

Skyline

Proteome Discoverer

Compound Discoverer

Job description

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a highly motivated Sr. Associate Scientist to join the Bioconjugate Analytics (BCA) team within the Analytical and Biological Mass Spectrometry (ABMS) Group. In this role, you will develop and apply LC-MS-based analytical methods to advance Regeneron's bioconjugate pipeline across all stages of development, including antibody-drug conjugates (ADCs), antibody-oligonucleotide conjugates (AOCs), antibody-tethered ligands (ATLs), and other emerging bioconjugate modalities. You will apply state-of-the-art mass spectrometry and analytical technologies to characterize bioconjugates and other therapeutic protein candidates, with a focus on critical quality attributes and process development, while collaborating closely with cross-functional teams to coordinate samples, study activities, priorities, and timelines. This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

When & Where: Shift Requirements: Full-time. Location: On-site in Tarrytown, NY.

What you’ll do:

• Develop and apply LC-MS-based analytical methods to characterize bioconjugates and other therapeutic protein candidates across R&D programs
• Perform sample preparation, LC-MS experiments, and data analysis using relevant software and bioinformatics tools to characterize product quality attributes; document results in electronic laboratory notebook (ELN) entries, presentations, and reports
• Support process development, R&D activities, and regulatory submissions through analytical characterization and scientific problem-solving
• Collaborate with cross-functional teams to understand analytical needs, coordinate samples and study activities, and align priorities, timelines, and deliverables
• Interpret and communicate scientific results through project and group meetings, technical reports, regulatory documents, internal and external conferences, and peer-reviewed publications

Must-haves:

• Master's degree with at least 3 years of relevant experience, or a Bachelor's degree with at least 6 years of relevant experience, in Chemistry, Biochemistry, Analytical Chemistry, Pharmaceutical Sciences, or a related field
• Industrial or academic experience in analytical characterization of protein therapeutics, bioconjugates, or other therapeutic modalities
• Strong knowledge of and hands‑on experience with LC‑MS‑based characterization of proteins, peptides, and bioconjugates (e.g., ADCs, AOCs, and ATLs), including sample preparation, liquid chromatography, mass spectrometry, and data analysis
• Enjoyment of developing and troubleshooting analytical methods and solving complex scientific and technical problems

Preferred / nice‑to‑haves:

• Experience with advanced mass spectrometer platforms (e.g., Orbitrap, Q-TOF, and triple quadrupole), liquid chromatography, and relevant data processing software (e.g., Protein Metrics, ChemDraw, Skyline, Proteome Discoverer, Compound Discoverer, and other related analytical tools)
• Thrive today. Grow tomorrow.

Benefits:

• Student Loan Paydown program & Tuition Reimbursement.
• Family Care Benefits.
• Relocation Assistance.
• Inclusion, Culture and Well-Being programs (including physical & mental health).
• Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits.
• For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/.

Equal Opportunity Employment

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship. Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits.

Salary Range (annually) $80,300.00 - $131,100.00.

About Regeneron

Regeneron is a leading biotechnology company that invents life-transforming medicines for people with serious diseases. Founded and led for over 30 years by physician-scientists, our unique ability to repeatedly and consistently translate science into medicine has led to nine FDA-approved treatments and numerous product candidates in development, almost all of which were homegrown in our laboratories. Our medicines and pipeline are designed to help patients with eye diseases, allergic and inflammatory diseases, cancer, cardiovascular and metabolic diseases, neurology, infectious diseases and rare diseases. Regeneron is also proud of award-winning culture of innovation, being recognized as a Great Place to Work in 2021, Fast Company’s Best Workplace for Innovators in 2020, and Forbes JUST companies in 2020, among others.

Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on‑site.