Spatial Biology Scientist, Lab Services (Boston)

Stellaromics Inc.; Boston (MA); On-site; USD 115,000 - 145,000; Full time

Job summary

Stellaromics is a Boston‑based biotech startup applying 3D spatial biology to map tissues and deliver actionable insights for researchers and clinicians. A hands‑on Scientist will design and run customer projects, optimize workflows, and translate complex results into recommendations for academic and biopharma partners.

The role emphasizes collaboration across Lab Services, R&D, and Field Applications, with a focus on high‑quality data, protocol development, and direct customer communication.

Qualifications

• BS with 10+ years, MS with 8+ years, or PhD in Chemistry, Biochemistry, Biophysics, Biomedical Engineering, Cell and Molecular Biology, or a related discipline with 6+ years experience.
• Hands‑on experience with tissue‑based molecular assays; experience in spatial biology, spatial transcriptomics, RNA-FISH, multiplexed immunofluorescence, or IHC is strongly preferred.
• Experience handling and optimizing workflows across multiple tissue types and sample‑preparation formats; experience with both FFPE and fresh frozen tissue is preferred.
• Strong foundation in molecular biology, tissue biology, microscopy, imaging, assay instrumentation, and quantitative data analysis.
• Demonstrated ability to design experiments, troubleshoot complex workflows, interpret results, and translate findings into actionable recommendations.
• Strong customer‑facing communication skills, including the ability to lead technical discussions, explain complex results clearly, and present recommendations to scientific audiences.
• Highly organized and able to manage multiple concurrent projects in a deadline‑driven service environment while maintaining attention to detail.
• Collaborative, self‑directed, and able to work effectively across laboratory, data, field, and commercial teams.
• Ability to learn new technologies quickly and contribute in a fast‑paced, evolving environment.
• Ability to work onsite full time in Boston, MA.

Responsibilities

• Develop and optimize new 3D spatial biology applications for a broad range of tissues and sample types.
• Design and execute customer studies from intake through data delivery, including feasibility assessment, experimental design, tissue preparation, assay execution, imaging, quality control, data analysis, and interpretation.
• Interact directly with academic and biopharma customers to understand research objectives, define project scope and success criteria, provide technical guidance, present results, and recommend next steps.
• Adapt and troubleshoot tissue-specific workflows and assay conditions to improve RNA quality, morphology preservation, staining performance, imaging quality, sensitivity, and reproducibility.
• Evaluate and interpret biochemical, imaging, 3D spatial transcriptomics, immunofluorescence/IHC, and H&E data; summarize findings in clear technical reports and customer presentations.
• Develop and maintain protocols, work instructions, application notes, and study reports that support reliable internal execution and customer adoption.
• Partner cross-functionally with Lab Services Operations, Assay R&D, Bioinformatics, Field Applications, and Commercial teams to incorporate customer feedback and transfer successful methods into repeatable service offerings.
• Manage multiple customer projects, maintain accurate experimental records, and communicate timelines, risks, and results proactively.
• Follow laboratory safety and quality procedures and contribute to continuous improvement of Lab Services workflows.
• Additional responsibilities may be assigned by management.

Skills

Spatial biology

RNA-FISH

Immunofluorescence

IHC

Tissue workflows

Experimental design

Data analysis

Customer-facing communication

Project management

Troubleshooting

Education

BS with 10+ years

MS with 8+ years

PhD with 6+ years

Job description

Stellaromics is a Boston‑based biotech startup applying 3D spatial biology to map tissues and deliver actionable insights for researchers and clinicians. A hands‑on Scientist will design and run customer projects, optimize workflows, and translate complex results into recommendations for academic and biopharma partners.

The role emphasizes collaboration across Lab Services, R&D, and Field Applications, with a focus on high‑quality data, protocol development, and direct customer communication.