Senior Software Engineer

Phia LLC; Boston, Northern (MA, KY); Hybrid; USD 71,000 - 144,000; Full time

Benefits offered by this job

Medical, dental & vision with employer

401K with 4% match

Disability insurance

FSA commuter benefits

PTO 20 days + 5 sick + 14 holidays

Employee Assistance Program

Job summary

SOPHiA GENETICS is seeking a Senior Software Engineer to join our Boston hybrid team. You will design, develop, and optimize scalable backend services and middleware for the SOPHiA DDM platform, integrating with hospital systems to process high volumes of medical data and deliver insights to oncologists.

You will work across the full stack spanning core components, public APIs, and middleware, with a focus on performance, cost-efficiency, and new integrations.

Qualifications

• 5+ years in a comparable software role with a degree (or higher).
• Proficient in Java for backend services and microservices experience.
• Experience with public APIs, API definitions and change management.
• Database design/optimisation with MySQL, MariaDB, DuckDB.
• Familiar with Linux and GitLab CI/CD pipelines.
• Knowledge of HL7/FHIR is a plus in healthcare data exchange.
• Able to optimize performance for large data volumes and cloud infra.
• Experience with scalable cloud architectures and containerized infra.
• Observability using Grafana/Loki; ability to monitor and troubleshoot.
• React.js is a plus for front-end work; Micronaut experience a plus.
• Kafka knowledge is beneficial; genomics experience valued.

Responsibilities

• Design, develop, and improve scalable, robust services within the architecture.
• Implement features across core components, API and middleware for new integrations.
• Support live integrations, propose enhancements for robustness based on feedback.
• Ensure performance under high workloads and optimize resource usage.
• Improve deployment workflows, CI/CD pipelines, and infra management.
• Maintain monitoring systems to track performance and bottlenecks.
• Leverage AI tools to boost productivity across workflows.

Skills

5+ years experience

Java backend

Microservices

Public APIs

Database design

AI tools & orchestration

HL7 & FHIR

Linux & GitLab

Performance optimization

Cloud & containerized infra

Observability (Grafana/Loki)

React.js (front-end)

Micronaut

Kafka

Genomics knowledge

Education

Bachelor or Master degree

Tools

Grafana

Loki

GitLab

Kafka

Micronaut

Job description

Are you an experienced Software Engineer with a passion for building and improving scalable, high-performance systems? Are you looking for a team that embraces fresh ideas, encourages an agile approach, and ensures your voice is heard and your contributions truly make an impact?

If this sounds like you and you are driven by purpose, join the SOPHiA GENETICS Software Engineering team as our new Senior Software Engineer, and enable us to make a positive impact on the outcomes for cancer and rare disease patients worldwide.

This is a hybrid opportunity, requiring 3 days onsite our corporate office in Boston, MA.

Our Mission

We believe there is a smarter, more data-driven way to make decisions in healthcare and our cloud-native AI powered SOPHiA DDM Platform makes that vision a reality on a daily basis. You will have direct input to our mission to democratize data-driven medicine for the ultimate benefit of cancer and rare disease patients across the globe.

Your Mission

As a Senior Software Engineer, you will be responsible for designing, developing, optimizing, and continuously improving software solutions, while contributing to technical initiatives and ensuring the solutions meet both business and technical requirements.

Your work will enable healthcare institutions in setting up diagnostic workflows that integrate seamlessly with the SOPHiA DDM platform – processing high-volume of medical data and bringing insights for oncologists via a streamlined process.

These components span the complete technology stack of SOPHiA DDM as well as the middleware layer responsible for integration and connectivity between SOPHiA DDM and external hospital systems. Your expertise will ensure these components not only scale effectively but also remain efficient in terms of performance and cost, while being extended with features required for new integrations.

The value you bring

• Design, develop, and continuously improve robust services that are scalable and efficient while fitting into overall system architecture
• Implement new features and enhancements across SOPHiA DDM core components, public API as well as middleware layer to enable setup of new integrations with external hospital systems of our customers
• Support existing live integrations with customers, propose and implement enhancements based on customer feedback and to achieve system robustness goals
• Ensure components perform reliably under high workloads, optimize system performance, resource utilization, and task execution times, contribute to improvements in system stability
• Optimize deployment workflows, automate pipelines, and enhance infrastructure management for efficient and reliable application deployment
• Implement and maintain monitoring systems to track performance and identify bottlenecks, use existing observability tools like Grafana and Loki to provide insights into operational health
• Use cutting edge AI tools and software engineering best practices to boost productivity across all workstreams

• Minimum of 5 years' experience in a comparable role, holding a bachelor’s or master’s degree (or higher)
• Solid proficiency in Java for backend services
• Solid understanding and extensive working experience with microservices architecture
• Solid experience with public APIs including API definition and change management
• Proficiency with databases like MySQL, MariaDB, and DuckDB, including design and query optimization
• Power user of latest AI tools and agent orchestration in all stages of software life cycle
• Knowledge of HL7 and FHIR standards for healthcare data exchange is a strong plus
• Familiarity with Linux environments and GitLab for version control and CI/CD pipelines
• Experience in optimization of system performance, manage resources effectively, and improve execution time – esp. when dealing with large data volumes
• Experience with scalable architecture, particularly in cloud environments and containerized infrastructure
• Familiarity with monitoring and observability tools such as Grafana and Loki
• React.js experience for front end development is a strong plus
• Experience with Micronaut for developing microservices and backend solutions is a strong plus.
• Knowledge of Kafka is a plus
• Experience in genomics is beneficial

US:

• Outstanding Medical, Dental & Vision with 90% Employer Contribution
• Company matched 401K at 4%
• Company-paid short & long-term disability insurance
• FSA commuter benefits
• 20 Days PTO, increasing to 25 with tenure; 5 Days Sick and 14 Public Holidays
• Free EAP

Our DNA

Like the strands of DNA itself, SOPHiA GENETICS and the team are deeply interconnected and reliant on each other to deliver. There are common threads across the team. Things that bind us together. Those things are Relentless Curious; Resilient & Nimble and Fearlessly Adventurous

Our Virtues

At SOPHiA GENETICS we established our 7 Virtues to clarify how our principles show up each day through action. We Decide; We Do; We Collaborate; We Innovate; We Empower; We Adapt and We Learn.

At the centre of our Virtues is our Mantra, We Care, which provides a constant reminder of the compassionate, benevolent, and hopeful nature of our mission and how it should be threaded through each of our Virtues and everything we do. Learn more about our DNA and Virtues on our Careers portal

The Process

We use the power of AI to help our partners make decisions. If you’re utilizing AI in your search and application process, why not use some of these prompts, or read our AI guide.

‘What impact can I expect to have on the world by working at SOPHiA GENETICS?’

‘I have an interview with SOPHiA GENETICS. What should I know before I meet with them?’

‘I am a *job title* - What can SOPHiA GENETICS offer my career?’

Suitably qualified candidates will be invited through an interview and screening process where you will speak with members of our Talent Acquisition Team, the hiring leader alongside key colleagues and stakeholders from across the business.

If you need additional support or accommodations for accessibility, please contact our TA team for assistance on [e-mail]. SOPHiA GENETICS recruiters only contact candidates from @sophiagenetics.com addresses and never request payment at any stage. Verify any offer before responding.

We appreciate the value external partners can bring, but we operate a direct-hiring model and we are not looking to utilize agency support at this time. All hiring is controlled by Talent Acquisition, potential partners should liaise through TA and not our hiring teams please.

Starting Date: ASAP

Location: Boston, MA - Hybrid 3x/week in office

Contract: Permanent

MA Pay Range: USD 71'250-143'750

Disclaimer:The estimated pay range represents a good faithestimate of what the Company expects to pay a successful applicant for the listed position andappliesspecificallyto candidates based in Massachusetts. Due to various factors, the estimated pay range may vary in other locations. Should the level or location of the role change during the hiring process, the applicable base range may be updated accordingly. Compensation decisions are dependent on several factors including, but not limited to, an individual’s qualifications, job related skills, years of experience, location, relevant education or training, internal equity, and alignment with market data. The range does not include benefits, and if applicable, bonus, commission, or equity.