Senior Secure HPC Administrator - Regulated Research Compute

American Medical Informatics Association, Inc; New York (NY); On-site; USD 113,000 - 202,000; Full time

Job summary

Mount Sinai Health System's Scientific Computing group seeks a Senior HPC Administrator to lead a secure, compliant high-performance computing environment supporting CMS/NIH data and regulated workloads. You will oversee a large-scale cluster and data ecosystem, ensuring audit-ready operations and stringent security controls.

The role requires deep technical expertise in computational systems, data platforms, and research software, with emphasis on cybersecurity, regulatory compliance, and

Qualifications

• 8+ years of progressive HPC systems administration experience in large-scale Linux batch environments.
• Hands-on experience with HPC schedulers, parallel file systems, configuration management (e.g., xCAT, Puppet, Ansible), databases, web services, Globus and high-performance networking (InfiniBand, Ethernet).
• Must be an expert troubleshooter; must be a team player and customer focused.
• Strong background in cybersecurity practices within regulated environments (e.g., healthcare, government), including firewalls, data protection, access controls, monitoring, and incident response.
• In-depth knowledge of NIST SP 800-171 and NIST SP 800-53, with hands-on experience implementing and operating compliant HPC systems.
• Script and programming experience
• Ability to manage multiple priorities effectively in a dynamic environment
• Excellent analytical ability, strong judgment and management skills, and the ability to work effectively as a liaison between both research and technology teams.
• Excellent written, verbal, and interpersonal communication skills.

Responsibilities

• Provide full lifecycle administration of secure HPC infrastructure including compute, storage, networking, and supporting services.
• Administer and support core HPC services such as job scheduling platforms (e.g., LSF), Open OnDemand user access environments, and PostgreSQL databases.
• Design, maintain, and enforce secure network architectures, including segmentation, firewall rules, and controlled ingress/egress.
• Lead the troubleshooting, isolation and resolution of all technical issues including system, hardware, software, and network.
• Implement and maintain NIST-aligned security controls, including encryption of data at rest and in transit, secure enclaves, access control, centralized logging, audit trails, and monitoring.
• Ensure continuous compliance with CMS DMP SAQ requirements, NIST SP 800-171/800-53 controls, NIH data governance policies, and Mount Sinai cybersecurity standards.
• Develop, maintain, and regularly update security policies, operational procedures, and technical documentation supporting regulatory compliance.
• Serve as the primary technical and process liaison with DTP Cybersecurity, GCO, and compliance stakeholders. Coordinate incident response activities and security investigations in partnership with DTP Cybersecurity.
• Organize and manage annual external audits and recertification efforts, ensuring timely remediation and sustained audit readiness.
• Stay current with emerging HPC and cybersecurity technologies to keep the organization’s infrastructure up-to-date.
• Work effectively and productively with other team members within the group and across Mount Sinai.
• Support researchers and users with computational, data, and analytics needs, including data transfers, software installation, batch jobs and troubleshooting etc. Answers and resolves user tickets. Create and update user-facing technical documentation for the CMS cluster.
• Provide after-hours support as needed.
• Perform other duties as assigned or requested.

Skills

HPC administration

Cybersecurity

NIST 800-171/800-53

Linux admin

Scripting

Regulatory compliance

Education

Bachelor's degree in CS/Engineering

Masters/PhD preferred

Tools

LSF

Open OnDemand

PostgreSQL

xCAT

Puppet

Ansible

GPFS Spectrum Scale

Globus

InfiniBand

Job description

Mount Sinai Health System's Scientific Computing group seeks a Senior HPC Administrator to lead a secure, compliant high-performance computing environment supporting CMS/NIH data and regulated workloads. You will oversee a large-scale cluster and data ecosystem, ensuring audit-ready operations and stringent security controls.

The role requires deep technical expertise in computational systems, data platforms, and research software, with emphasis on cybersecurity, regulatory compliance, and