Senior Scientist, Yeast Display & Antibody Discovery

Xencor; Pasadena (CA); On-site; USD 118,000 - 150,000; Full time

Benefits offered by this job

401k match

Healthcare coverage

ESPP

Job summary

Xencor, Inc. in Pasadena, CA, is seeking a Scientist 2 in the Antibody Discovery team. The role emphasizes yeast display-based discovery campaigns, library design, and collaboration across functions to identify novel therapeutic hits and optimize leads.

The candidate will work in vitro and contribute to data generation, analysis, and decision making. Ideal candidates have a Ph.D. with 3+ years of post-graduate experience, strong cloning, NGS, and developability insight, and a track record of

Qualifications

• Ph.D. in a relevant scientific field with at least 3 years of post-graduate laboratory work experience.
• Experience with yeast display and library design.
• Experience with NGS library generation, QC, sequencing and analysis.
• Strong communication and collaboration within cross-functional teams.

Responsibilities

• Perform yeast display-based discovery screens to support programs.
• Use NGS for hit selection and data analysis.
• Lead/optimize display libraries and process.
• Stay current with advances in yeast display and related fields.
• Coordinate with other departments to prioritize experiments.
• Present data in group and departmental meetings.
• Maintain laboratory safety and protocols.
• Contribute to experimental design, data interpretation, and record-keeping.
• Provide mentorship to junior personnel as needed.

Skills

Yeast display

NGS

Antibody engineering

Molecular cloning

Data analysis

Team collaboration

High-throughput screens

Benchling ELN

Education

Ph.D. in a relevant scientific field

Tools

Geneious Prime

Sequencher

Job description

Xencor, Inc. in Pasadena, CA, is seeking a Scientist 2 in the Antibody Discovery team. The role emphasizes yeast display-based discovery campaigns, library design, and collaboration across functions to identify novel therapeutic hits and optimize leads.

The candidate will work in vitro and contribute to data generation, analysis, and decision making. Ideal candidates have a Ph.D. with 3+ years of post-graduate experience, strong cloning, NGS, and developability insight, and a track record of