Senior Scientist: Translational MPS & Automated Cell Culture

Novartis AG; Cambridge (MA); On-site; USD 94,000 - 183,000; Full time

Benefits offered by this job

Health benefits

401(k) with company match

Generous time off

Job summary

Novartis BioMedical Research in Cambridge, MA seeks a Senior Scientist I/II to advance translational preclinical models. The role focuses on manual and automated tissue culture, human model systems, and scalable workflows across automated platforms to deliver reliable data.

You will collaborate with scientists to optimize protocols, troubleshoot, and generate well-characterized cellular models for drug discovery and translational research programs.

Qualifications

• Hands-on experience maintaining mammalian cell cultures, including iPSC/cancer lines, with aseptic technique.
• Experience executing cell culture or differentiation workflows with reproducibility, scheduling, and documentation.
• Experience designing, building, deploying, operating, or troubleshooting automated laboratory workflows.
• Working knowledge of microscopy, image-based monitoring, and quantitative data analysis for cellular models.
• Strong organizational, written, and verbal communication skills; able to work independently and across teams.

Responsibilities

• Maintain, expand, cryopreserve, and characterize human pluripotent stem cell lines (iPSC, hESC).
• Execute multiple stem cell differentiation protocols in parallel with traceable documentation.
• Perform large-scale iPSC culture using automated liquid-handling platforms and high-throughput robotic systems.
• Program, operate, calibrate, and troubleshoot automated tissue culture platforms (CellTrio, HighRes Biosolutions).
• Develop microscopy and image-analysis workflows to monitor cell health and enable data-driven decisions.

Skills

Cell culture

Automation

Microscopy

Image analysis

Data interpretation

Scheduling

Documentation

Team collaboration

Education

B.S./M.S. in Cell Biology or related field

Recent PhD graduates considered

Job description

Novartis BioMedical Research in Cambridge, MA seeks a Senior Scientist I/II to advance translational preclinical models. The role focuses on manual and automated tissue culture, human model systems, and scalable workflows across automated platforms to deliver reliable data.

You will collaborate with scientists to optimize protocols, troubleshoot, and generate well-characterized cellular models for drug discovery and translational research programs.