Senior Translational Immuno-Oncology Scientist - Onsite

Novartis AG; Cambridge (MA); On-site; USD 130,000 - 170,000; Full time

Benefits offered by this job

Health, life and disability benefits

401(k) with company match

Vacation and holidays

Personal days

Parental leave (minimum 14 weeks)

Hybrid working options

Job summary

Novartis Biomedical Research in Cambridge, MA invites applications for Senior Scientist I/II in Oncology Translational Research. You will lead hands-on flow cytometry and immune cell assays, translating hypotheses into actionable experiments, collaborating across functional teams.

Ideal candidates have 5+ years (Bachelor) or 3+ years (Master) in relevant biology, with expertise in multiparameter flow cytometry, primary cell culture, and immunology assays.

Qualifications

• This role requires advanced hands-on experience with multiparameter or spectral flow cytometry including panel design and analysis.
• Experience with primary human cell culture and immune or tumor biology assays, including co-cultures.
• Experience with intracellular cytokine staining and multiplex cytokine assays to quantify PD responses.
• Strong data-analysis and presentation skills enabling clear, decision-ready figures and reports.
• Ability to independently design, troubleshoot, and execute rigorous experiments.

Responsibilities

• Design, develop, and optimize flow cytometry and cell-based assays across hematologic and solid tumors.
• Execute ex vivo studies using human cells and patient-derived materials with sterile techniques.
• Develop readouts for proliferation, viability, apoptosis, and cytokine signaling.
• Analyze and integrate data; communicate interpretations and next steps to project teams.
• Plan experiments aligned with strategy; manage priorities and deliver reproducible data.

Education

Bachelor’s degree in cell biology, molecular biology or immunology

Master’s degree in a related discipline

Tools

GraphPad Prism

Spotfire

IncuCyte

Job description

Novartis Biomedical Research in Cambridge, MA invites applications for Senior Scientist I/II in Oncology Translational Research. You will lead hands-on flow cytometry and immune cell assays, translating hypotheses into actionable experiments, collaborating across functional teams.

Ideal candidates have 5+ years (Bachelor) or 3+ years (Master) in relevant biology, with expertise in multiparameter flow cytometry, primary cell culture, and immunology assays.