Senior Scientist – Automated iPSC & MPS Platforms

Novartis Group Companies; Cambridge (MA); On-site; USD 94,000 - 183,000; Full time

Job summary

Novartis BioMedical Research in Cambridge, MA, is seeking a Senior Scientist I/II to lead manual and automated tissue culture and human model systems. You will operate, maintain, troubleshoot, and develop scalable workflows across automation platforms to deliver reliable, well-characterized cell models.

Collaborate with cross-functional teams to design experiments, optimize MPS-based studies, and translate data into actionable insights for drug discovery and translational research.

Qualifications

• B.S./M.S. in Cell Biology, Molecular Biology, Biochemistry, Bioengineering, or related field with 4+ years of experience; PhD candidates considered
• Hands-on experience maintaining mammalian cell cultures with good aseptic technique
• Experience designing, building, deploying, or troubleshooting automated lab workflows
• Strong microscopy and image-analysis skills with data-driven decision making

Responsibilities

• Maintain and expand pluripotent stem cell lines (iPSC, hESC); cryopreserve and characterize lines
• Execute multiple stem cell differentiation protocols and maintain schedules and documentation
• Operate large-scale automated tissue culture platforms; troubleshoot and optimize workflows
• Develop and apply microscopy and image-analysis workflows for real-time monitoring
• Establish and operate organ-on-chip models and 3D tissue cultures; document data
• Design and optimize MPS-based studies with cross-functional teams
• Create, refine SOPs and maintenance procedures; train users and coordinate production needs

Skills

Cell culture

Stem cell biology

Automation workflows

Microscopy

Image analysis

Project collaboration

Documentation

Scheduling

Education

B.S./M.S. in Cell Biology, Molecular Biology, Biochemistry, Bioengineering, or related

PhD (recent graduates considered)

Tools

CellTrio

HighRes Biosolutions

Sartorius CompacT

Genedata Screener

Spotfire

Job description

Novartis BioMedical Research in Cambridge, MA, is seeking a Senior Scientist I/II to lead manual and automated tissue culture and human model systems. You will operate, maintain, troubleshoot, and develop scalable workflows across automation platforms to deliver reliable, well-characterized cell models.

Collaborate with cross-functional teams to design experiments, optimize MPS-based studies, and translate data into actionable insights for drug discovery and translational research.