Senior Scientist: Translational MPS & Automated Culture

U175 (FCRS = US175) Novartis Institutes for BioMedical Research, Inc.; Cambridge (MA); On-site; USD 94,000 - 183,000; Full time

Benefits offered by this job

Health benefits

401(k) with company match

Other benefits

Generous time off

Job summary

Novartis Institutes for BioMedical Research, Cambridge, MA, is seeking a Senior Scientist I/II to lead manual and automated tissue culture and human model systems. You will operate, maintain, and troubleshoot scalable workflows across automated platforms, collaborating with scientists to deliver reproducible cellular models for drug discovery.

The role emphasizes expertise in cell biology, automation software, imaging, and data interpretation, with a focus on scalable, translational models and

Qualifications

• B.S. or M.S. in Cell Biology, Molecular Biology, Biochemistry, Bioengineering, or related discipline with 4+ years post-grad experience.
• Recent PhD graduates within last 2 years with relevant experience may be considered.
• Hands-on experience maintaining mammalian cell cultures, including human cancer cell lines and/or iPSCs, with aseptic technique.
• Experience performing cell culture or differentiation workflows with reproducibility, scheduling, documentation, and quality control.
• Experience designing, building, deploying, or troubleshooting automated lab workflows in life science or clinical settings.
• Knowledge of microscopy, image-based monitoring, and quantitative data analysis for cellular models.

Responsibilities

• Maintain and characterize human pluripotent stem cell lines (iPSC/hESC).
• Execute multiple stem cell differentiation protocols with schedules and documentation.
• Scale iPSC culture using automated platforms and high-throughput robotics.
• Program and troubleshoot automated tissue culture platforms (CellTrio, HighRes cells).
• Develop microscopy and image-analysis workflows to monitor cell health.
• Operate microphysiological systems and organ-on-chip models.
• Support cross-functional studies to improve data quality and translational relevance.
• Create and update SOPs, maintenance manuals, and start-up procedures.

Skills

Stem cell culture

Automated workflows

Microscopy

Cell differentiation

Image analysis

Data interpretation

Education

Bachelor/Master in Cell Biology or related

PhD considered

Tools

CellTrio RoboCell

HighRes Biosolutions

Sartorius CompacT

Liquid handlers

Job description

Novartis Institutes for BioMedical Research, Cambridge, MA, is seeking a Senior Scientist I/II to lead manual and automated tissue culture and human model systems. You will operate, maintain, and troubleshoot scalable workflows across automated platforms, collaborating with scientists to deliver reproducible cellular models for drug discovery.

The role emphasizes expertise in cell biology, automation software, imaging, and data interpretation, with a focus on scalable, translational models and