Senior Scientist: Surface Target Modality Discovery

BioSpace; Thousand Oaks (CA); On-site; USD 140,000 - 190,000; Full time

Benefits offered by this job

Retirement plan

Medical, dental, vision coverage

Life and disability insurance

Flexible spending accounts

Bonus program

Job summary

Amgen seeks a Senior Scientist for Therapeutic Modality Assessment in Surface Biology. You will triage proteomics/transcriptomics hits to define actionable target properties and guide early modality selection.

You will conduct quantitative surface target characterization and evaluate modalities, informing prioritization strategies. The role requires PhD in cell biology with industry experience, strong data analysis, and hands-on HTS/flow cytometry expertise.

Qualifications

• Ph.D. in Cell Biology or related field with 2+ years of industry experience preferred.
• Strong background in cell-surface biology and therapeutic modality evaluation.
• Experience with HTS assays and cell-based readouts.

Responsibilities

• Propose therapeutic modalities for surface targets and define experimental strategies.
• Develop and execute scalable, high-throughput workflows to evaluate target modulation.
• Integrate findings into Go/No-Go decision packages to guide modality selection.
• Collaborate across teams and document workflows with validated data.

Skills

Flow cytometry

High‑throughput screening

Data analysis

Experimental design

Cell biology

Education

Ph.D. in Cell Biology

Tools

Echo

Tecan

Hamilton

Job description

Amgen seeks a Senior Scientist for Therapeutic Modality Assessment in Surface Biology. You will triage proteomics/transcriptomics hits to define actionable target properties and guide early modality selection.

You will conduct quantitative surface target characterization and evaluate modalities, informing prioritization strategies. The role requires PhD in cell biology with industry experience, strong data analysis, and hands-on HTS/flow cytometry expertise.