Senior Scientist, Protein Dynamics Data Architect

Astera Institute

Emeryville (CA)

Presencial

USD 220.000 - 260.000

Tempo integral

14 dias+

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Benefícios oferecidos por esta vaga

Health insurance
Daily lunch
AI tool licenses
403(b) plan
Flexible PTO
Visa sponsorship

Resumo da vaga

Astera Institute in Emeryville, CA seeks a Senior Scientist, Structural Data Representation to lead encoding of conformational ensembles and connect them to visualization, ML, and computational pipelines. You will head a small Prism team and collaborate with external developers to standardize ensemble data for the field.

You will design encoding models, build databases, support native integration with open-source structural biology tools, and partner with PDB and others to advance public-good

Qualificações

  • PhD in a relevant area; at least 4 years of work experience.
  • Experience managing a team of scientists or engineers.
  • Deep understanding of how structural models are encoded and used for interpretation, including fluency in mmCIF and its extension mechanisms.
  • Strong coding experience, with a track record of writing software that other people use.
  • Clear communication across technical communities; can explain data standards to structural biologists, ML researchers, and software developers.
  • Execution-forward approach; ships working versions, gathers feedback, and iterates.
  • Nice to have: product development experience.
  • Nice to have: experience building scientific databases or visualization tools.

Responsabilidades

  • Lead and mentor a team of 2-3 scientists and software engineers, setting priorities and maintaining execution as ensemble models move to broad adoption.
  • Work with the Scientific Program Director to determine strategy and prioritization of approaches and science within your team.
  • Partner with Prism's modeling and ensemble-functional team to ensure cohesion and data representation supports downstream analyses.
  • Design, test, and deploy encoding models and schemas for conformational ensembles.
  • Direct the development of databases to connect dynamic ensemble models for data sharing and downstream use, including visualization tools.
  • Collaborate with external partners such as the PDB and tool developers to bridge Prism with external work.
  • Partner with teams behind open-source tools to implement native support for ensemble models.

Conhecimentos

Team management
mmCIF proficiency
Software development
Cross-community communication
Execution mindset

Formação

PhD in a relevant area

Descrição da vaga

Astera Institute in Emeryville, CA seeks a Senior Scientist, Structural Data Representation to lead encoding of conformational ensembles and connect them to visualization, ML, and computational pipelines. You will head a small Prism team and collaborate with external developers to standardize ensemble data for the field.

You will design encoding models, build databases, support native integration with open-source structural biology tools, and partner with PDB and others to advance public-good

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