Senior Scientist, NAMs & In Vitro Toxicology

Merck & Co.; West Point (PA); On-site; USD 106,000 - 167,000; Full time

Benefits offered by this job

Medical insurance

Dental insurance

Vision insurance

401(k)

Paid holidays

Vacation days

Sick days

Job summary

Merck & Co., Inc. in the United States is seeking a Senior Scientist to advance NAMs and investigative toxicology using cutting-edge in vitro models such as 3D tissues and organoids.

The role emphasizes strategic thinking, collaboration across disciplines, and leadership in translating complex science to stakeholders. The candidate will design mechanistic studies, develop translational biomarkers, and contribute to safety assessment strategies, while publishing findings and representing the

Qualifications

• Ph.D. in relevant life sciences field.
• Demonstrated experience in cell-based assay development and complex in vitro model systems.
• Strong record of scientific achievement through publications, presentations, or equivalent contributions.

Responsibilities

• Develop, qualify and implement advanced in vitro assays and human-relevant model systems to support investigative toxicology and nonclinical safety assessment.
• Design and execute mechanistic studies to evaluate drug effects, toxicity mechanisms, and translational biomarkers.
• Synthesize complex scientific data and communicate key insights clearly to multidisciplinary teams, leadership, and non-technical stakeholders.
• Evaluate emerging technologies and identify opportunities to advance scientific capabilities and decision-making.
• Collaborate across internal and external partners in discovery, safety assessment, drug metabolism, and translational sciences.
• Contribute to scientific strategy related to NAMs, MPS, and next-generation safety assessment approaches.
• Publish findings and represent the organization through scientific presentations and collaborations.

Skills

Cell-based assays

In vitro model systems

Scientific publications

Education

Ph.D. in Cell Biology, Toxicology, Pharmacology, Biomedical Engineering, Bioengineering, Molecular Biology, Pharmaceutical Sciences, or related discipline

Job description

Merck & Co., Inc. in the United States is seeking a Senior Scientist to advance NAMs and investigative toxicology using cutting-edge in vitro models such as 3D tissues and organoids.

The role emphasizes strategic thinking, collaboration across disciplines, and leadership in translating complex science to stakeholders. The candidate will design mechanistic studies, develop translational biomarkers, and contribute to safety assessment strategies, while publishing findings and representing the