Senior Scientist, Molecular Biology

Scorpion Therapeutics; California (MO); On-site; USD 120,000 - 180,000; Full time

Job summary

Gilead is seeking a Lead Scientist in Molecular Biology within the Protein Therapeutics group. The role focuses on designing high-throughput recombinant protein expression workflows for therapeutic programs spanning virology, inflammation, and oncology.

The candidate will oversee plasmid development, advance automation, manage CRO partnerships, and contribute to publications and patents while mentoring the team in a laboratory setting.

Qualifications

• PhD with 3+ years postdoc or industry experience, or equivalent (e.g., BS + 15+ years, MS + 12+ years).
• Extensive expertise in molecular cloning and DNA assembly methods (Gibson, Golden Gate, In-Fusion).
• Experience with automation platforms, DNA repository management, and CRO oversight for sequence verification and data accuracy.
• Proficiency in bioinformatics tools and scripting languages is preferred.

Responsibilities

• Oversee plasmid and expression construct development using multiple DNA assembly technologies.
• Enhance automation and integrate robotic systems to improve capacity and reduce cycle times.
• Manage external CRO collaborations for sequence verification and data accuracy.
• Develop standardized digital workflows aligned with research informatics.
• Maintain and improve a scalable DNA repository.
• Contribute to scientific publications and patent filings; mentor team members and present findings to stakeholders.

Skills

Molecular cloning

DNA assembly

High-throughput workflows

Automation platforms

Bioinformatics

Scripting

Education

PhD in molecular/cell biology

Tools

DNA repository management

Automation platforms

External CRO oversight

Job description

Role: Lead scientist in Molecular Biology within Gilead's Protein Therapeutics department, focusing on designing and optimizing high-throughput recombinant protein expression workflows for therapeutic programs in Virology, Inflammation, and Oncology.

Responsibilities

oversee complex plasmid and expression construct development using various DNA assembly technologies; enhance automation and integrate robotic systems to improve capacity and reduce cycle times; manage external CRO collaborations for sequence verification and data accuracy; develop standardized digital workflows aligned with research informatics; maintain and improve a scalable DNA repository; contribute to scientific publications and patent filings; mentor team members and present findings to stakeholders.

Requirements

Ph.D. in molecular/cell biology or related fields with 3+ years postdoctoral or industry experience, or equivalent industry experience (e.g., BS + 15+ years, MS + 12+ years); extensive expertise in molecular cloning, DNA assembly methods (Gibson, Golden Gate, In-Fusion), and high-throughput workflows; experience with automation platforms, DNA repository management, and external CRO oversight; proficiency in bioinformatics tools and scripting languages preferred.

High-Value

biologics discovery, gene-to-protein platform, recombinant expression, team leadership, cross-functional collaboration, and automation integration.

WorkSetup

not specified, but likely in a laboratory setting with cross-functional interaction.