Senior Scientist, Lipid Nanoparticle & RNA Delivery

CSL; Waltham (MA); On-site; USD 126,000 - 157,000; Full time

Benefits offered by this job

Onsite role in Waltham

Competitive compensation package

Job summary

CSL in Waltham, MA seeks a Senior Scientist, Delivery Technologies to advance lipid nanoparticle delivery and RNA therapeutics. You will design, formulate, and characterize delivery systems across cross-functional teams, mentoring junior scientists.

The role emphasizes extrahepatic LNPs, siRNA conjugates, and translational drug delivery science with in vitro and in vivo evaluation, DOE, and scale-up considerations.

Qualifications

• PhD or MS with strong background in drug delivery and LNP formulation.
• Experience leading cross-functional research projects and teams.
• Proven track record in nanoparticle formulation and delivery sciences.
• Expertise in RNA-based delivery systems and translational science.

Responsibilities

• Lead design, formulation, and characterization of LNPs with RNA cargoes.
• Apply DOE principles to formulation screening and optimization.
• Develop targeted delivery (t-LNP) strategies for extrahepatic tissues.
• Evaluate delivery performance in vitro and in vivo and assess biodistribution.
• Mentor junior scientists and collaborate across research, development, and manufacturing.

Skills

LNP formulation

Nanoparticle characterization

In vitro and in vivo evaluation

Design of Experiments (DOE)

Targeted extrahepatic delivery

Education

PhD in Pharmaceutical Sciences

MS in Pharmaceutical Sciences

Job description

CSL in Waltham, MA seeks a Senior Scientist, Delivery Technologies to advance lipid nanoparticle delivery and RNA therapeutics. You will design, formulate, and characterize delivery systems across cross-functional teams, mentoring junior scientists.

The role emphasizes extrahepatic LNPs, siRNA conjugates, and translational drug delivery science with in vitro and in vivo evaluation, DOE, and scale-up considerations.