Senior Scientist, Drug Delivery

Proforma Health; Waltham (MA); On-site; USD 90,000 - 130,000; Full time

Job summary

Proforma Health Inc in Waltham, MA is seeking a scientist to design, formulate, characterize, and optimize lipid nanoparticle (LNP) and related delivery systems for nucleic-acid therapeutics. You will lead research on targeted delivery and siRNA conjugates, advancing formulation and functional performance.

Responsibilities include developing delivery platforms, performing characterization, evaluating in vitro and in vivo performance, and collaborating with cross-functional teams across R&D and

Qualifications

• Strong expertise in lipid-based drug delivery and nucleic-acid therapeutic systems.
• Experience with targeted delivery and siRNA-conjugate approaches.
• Ability to execute and analyze in vitro and in vivo performance studies.
• Demonstrated collaboration skills in cross-functional scientific environments.

Responsibilities

• Develop and refine LNP and related delivery platforms for nucleic-acid therapeutics.
• Perform characterization and optimization to improve delivery efficiency and targeting.
• Evaluate performance of delivery systems in vitro and in vivo models.
• Conduct and interpret experimental studies to guide design decisions.
• Collaborate with cross-functional teams across research, development, and manufacturing.

Skills

Lipid-based delivery

Nucleic-acid therapeutics

Targeted delivery

siRNA conjugates

In vitro & in vivo studies

Cross-functional collaboration

Job description

Role Summary

Design, formulate, characterize, and optimize lipid nanoparticle (LNP) and other delivery systems for nucleic-acid therapeutics. Lead research on targeted delivery and siRNA conjugates, advancing formulation and functional performance.

Key Responsibilities

• Develop and refine LNP and related delivery platforms for nucleic-acid therapeutics.
• Perform characterization and optimization to improve delivery efficiency and targeting.
• Evaluate performance of delivery systems in vitro and in vivo models.
• Conduct and interpret experimental studies to guide design decisions.
• Collaborate with cross-functional teams across research, development, and manufacturing.

Qualifications & Skills

• Strong expertise in lipid-based drug delivery and nucleic-acid therapeutic systems.
• Experience with targeted delivery and siRNA-conjugate approaches.
• Ability to execute and analyze in vitro and in vivo performance studies.
• Demonstrated collaboration skills in cross-functional scientific environments.