Senior Scientist, iPSC Cell Therapy Platform

QLD Biotherapeutics Inc; Boston (MA); On-site; USD 120,000 - 180,000; Full time

Job summary

QLD Biotherapeutics Inc. is seeking a Scientist/Senior Scientist to join the Cellular Therapy Group in Boston. The role focuses on developing iPSC-derived differentiation platforms and advancing cell therapies for diabetes and neurological diseases.

The candidate will collaborate with a drug discovery team to drive early R&D activities, optimize scalable workflows, and contribute to IND-enabling work in a fast-paced, team-oriented environment.

Qualifications

• PhD in developmental biology, immunology, cell biology, or related field with 3+ years of post‑doctoral, academic faculty, or industrial experience.
• Expertise at iPSC or stem cell differentiation, culture, banking and characterization.
• Experience with CRISPR, lentivirus, transposon and LNP delivery preferred.
• Experience with multiplex flow cytometry and whole genome sequencing preferred.
• Strong publication record and excellent communication skills.

Responsibilities

• Design and optimize iPSC differentiation platforms to produce beta-islet and neuronal cells with high purity.
• Develop and validate characterization assays across differentiation stages.
• Reprogram somatic/blood cells and bank iPSC clones.
• Analyze data and communicate results to project teams in a timely manner.
• Manage study progress, ensure data accuracy and integrity.
• Prepare preclinical documents and patent-related studies to support IND filing.
• Identify hurdles and contribute to contingency plans with cross-functional teams.
• Adhere to SOPs and GxP guidelines in a collaborative environment.

Skills

iPSC differentiation

Stem cell culture & banking

CRISPR / gene engineering

Flow cytometry

Whole genome sequencing

Scientific communication

Education

PhD in developmental biology / immunology / cell biology or related

Tools

CRISPR

Lentivirus

Transposon

LNP delivery

Job description

QLD Biotherapeutics Inc. is seeking a Scientist/Senior Scientist to join the Cellular Therapy Group in Boston. The role focuses on developing iPSC-derived differentiation platforms and advancing cell therapies for diabetes and neurological diseases.

The candidate will collaborate with a drug discovery team to drive early R&D activities, optimize scalable workflows, and contribute to IND-enabling work in a fast-paced, team-oriented environment.