Senior Scientist, Immunology & RNA‑LNP Cell Therapies

C10 Labs; Cambridge (MA); On-site; USD 120,000 - 180,000; Full time

Job summary

Noara Therapeutics, Cambridge, MA, is seeking a Senior Scientist or Scientist with deep expertise in cell biology, immunology, and assay development to lead the design and execution of cell-based and immunology assays that drive therapeutic discovery.

This laboratory-based role offers opportunities to shape experimental strategy, establish new capabilities, and collaborate with molecular biology, computational biology, automation, and data science teams to develop scalable assays for our RNA‑LNP

Qualifications

• Ph.D. in Immunology, Cell Biology, Molecular Biology, or a related discipline.
• For Scientist candidates: 3+ years of relevant industry experience; biotechnology or startup experience is preferred.
• For Senior Scientist candidates: 5+ years of relevant industry experience with demonstrated scientific leadership; biotechnology or startup experience is preferred.
• Demonstrated expertise in designing, developing, and optimizing complex cell‑based assays.
• Extensive hands‑on experience with flow cytometry and FACS, including multicolor panel design and cell sorting.
• Strong experience working with human primary cells, particularly primary immune cells.
• Experience with RNA‑LNP delivery systems and/or engineered cell therapies (including CAR‑based platforms or related technologies).
• Proven ability to independently lead assay development from concept through implementation.
• Excellent experimental troubleshooting, analytical, and scientific communication skills.
• Ability to thrive in a dynamic, fast‑paced startup environment where adaptability, initiative, and collaboration are essential.

Responsibilities

• Design, develop, optimize, and execute cell‑based and immunology assays to evaluate candidate potency, cytotoxicity, and biological activity.
• Perform and optimize reporter assays, flow cytometry, and fluorescence‑activated cell sorting (FACS) for cellular characterization and functional assessment.
• Culture, engineer, and characterize human primary cells, with particular emphasis on immune cell populations.
• Prepare, deliver, and evaluate RNA‑LNP formulations in relevant cellular systems.
• Develop scalable, plate‑based assay workflows suitable for high‑throughput experimentation, including assay miniaturization, troubleshooting, and SOP development.
• Collaborate closely with molecular biology, computational biology, machine learning, and automation teams to generate high‑quality datasets for downstream analysis and model development.
• Contribute to the establishment of laboratory infrastructure, experimental standards, and best practices.
• Mentor junior scientists and foster a collaborative, scientifically rigorous research environment.

Skills

Flow cytometry

FACS

Cell-based assays

RNA‑LNP delivery systems

Scientific leadership

Data analysis

Education

Ph.D. in Immunology or related field

Tools

Flow cytometer (instrument)

Automation platforms

Job description

Noara Therapeutics, Cambridge, MA, is seeking a Senior Scientist or Scientist with deep expertise in cell biology, immunology, and assay development to lead the design and execution of cell-based and immunology assays that drive therapeutic discovery.

This laboratory-based role offers opportunities to shape experimental strategy, establish new capabilities, and collaborate with molecular biology, computational biology, automation, and data science teams to develop scalable assays for our RNA‑LNP