Nonclinical Research Scientist - Senior/Associate

Pioneering Medicines; Cambridge (MA); On-site; USD 81,000 - 127,000; Full time

Benefits offered by this job

Healthcare coverage

Annual incentive program

Retirement benefits

Broad range of benefits

Job summary

Alltrna in Cambridge, MA is seeking a hands-on Senior Research Associate/Associate Scientist for Nonclinical work. You will design and optimize cell-based assays to measure tRNA activity and support IND-enabling studies, handling DNA/RNA delivery and biomarker readouts.

The role requires a strong background in mammalian cell culture, molecular biology, and data analysis, with collaboration across the Nonclinical team to advance early programs toward clinical development.

Qualifications

• BS or MS in biology, biochemistry, pharmacology, or a related field.
• Minimum BS with 4+ years or MS with 2+ years of hands-on laboratory experience in academia, biotech, or pharma.
• Strong experience in mammalian cell culture and molecular assays.

Responsibilities

• Design, optimize, validate, and implement cell-based assays to support early-stage discovery and IND-enabling studies.
• Execute in vitro and in vivo sample processing to support nonclinical studies per SOPs.
• Conduct biomarker-related assays and analyze data for study decisions.
• Document experiments in ELN with data integrity and traceability.
• Collaborate across teams to share results and drive project timelines.

Skills

Cell culture

PCR/qPCR

Western blot

Flow cytometry

Molecular assays

Data interpretation

Team collaboration

Education

BS or MS in biology/biochemistry/pharmacology or related

Tools

CRISPR

Lentiviral/AAV transduction

qPCR machines

ELN

Job description

Alltrna in Cambridge, MA is seeking a hands-on Senior Research Associate/Associate Scientist for Nonclinical work. You will design and optimize cell-based assays to measure tRNA activity and support IND-enabling studies, handling DNA/RNA delivery and biomarker readouts.

The role requires a strong background in mammalian cell culture, molecular biology, and data analysis, with collaboration across the Nonclinical team to advance early programs toward clinical development.