Senior Scientist – IHC-Driven Companion Diagnostics

SystImmune; Redmond (WA); Vor Ort; USD 90.000 - 140.000; Vollzeit

Benefits dieser Stelle

Premium benefits

401(k) match

Paid time off

Holidays & sick leave

Zusammenfassung

SystImmune in Redmond, WA, seeks a Scientist/Senior Scientist to lead end-to-end IHC assay development for CDx kits in oncology drug development. You will select antibodies, optimize assays, validate performance, and implement in clinical trials, working with CROs and central labs.

The role requires deep pathology/IHC expertise, cross-functional collaboration, and regulatory alignment to move RUO/LDT toward IVD CDx commercialization. Competitive salary and comprehensive benefits offered.

Qualifikationen

• PhD in Pathology, Molecular Biology, Immunology, Oncology, or a related field.
• 3–5+ years of hands-on IHC assay development in CDx/IVD settings.
• IHC scoring methods such as TPS, H-score, CPS.
• Familiar with regulatory expectations for CDx.
• Strong collaboration across R&D, clinical, regulatory, QA and CROs.

Aufgaben

• Lead development of IHC-based CDx assays from discovery through validation.
• Select and evaluate primary antibodies, detection systems and platforms (Ventana, Dako, Leica).
• Optimize assay parameters and establish scoring cut-offs with pathologists.
• Support regulatory documentation and CDx readiness for trials.
• Coordinate with CROs, central labs and external partners.

Kenntnisse

IHC assay development

CDx regulatory knowledge

Cross-functional collaboration

Biomarker strategies

Data interpretation

Ausbildung

PhD in Pathology or related

MS/BS with CDx/IVD experience

Tools

Ventana

Dako

Leica

Jobbeschreibung

SystImmune in Redmond, WA, seeks a Scientist/Senior Scientist to lead end-to-end IHC assay development for CDx kits in oncology drug development. You will select antibodies, optimize assays, validate performance, and implement in clinical trials, working with CROs and central labs.

The role requires deep pathology/IHC expertise, cross-functional collaboration, and regulatory alignment to move RUO/LDT toward IVD CDx commercialization. Competitive salary and comprehensive benefits offered.