Senior Scientist I - Bioanalytics

AbbVie Inc.; North Chicago (IL); On-site; USD 120,000 - 180,000; Full time

Benefits offered by this job

Short-term incentive programs

Job summary

AbbVie Inc. in the United States seeks a Senior Scientist to lead regulated bioanalysis in the QTAS department.

You will manage projects across the bioanalytical lifecycle, supervise workflows, review data, and author reports for GLP non-clinical and clinical studies, collaborating across preclinical safety and clinical pharmacology. The role demands experience in regulated environments, method development/validation for diverse molecules, and strong problem-solving within mass spectrometry

Qualifications

• Experience with regulated bioanalysis in drug development.
• Knowledge of ALCOA principles and regulatory guidelines.
• Development/validation of bioanalytical methods for small, large molecules and peptides.
• Experience operating AB Sciex MS platforms or equivalents.
• Familiarity with LIMS and related software.
• Experience with Shimadzu LC instruments and automated systems.
• Strong collaboration and project management skills.

Responsibilities

• Oversee sample analysis for nonclinical and clinical trials per regulatory requirements.
• Manage internal/external stakeholders on deliverables and priorities.
• Monitor trends in separations and mass spectrometry.
• Maintain and troubleshoot LC systems and mass spectrometers.
• Author/approve method documents for regulated analysis and publications.
• Provide expertise in cutting-edge assay technologies and troubleshooting.

Skills

Bioanalytical operations

Regulatory compliance

Mass spectrometry

Assay troubleshooting

Project management

Interpersonal skills

Education

Ph.D. in Analytical Chemistry or related field

M.S. in Analytical Chemistry or related field

B.S. in Analytical Chemistry or related field

Tools

AB Sciex triple quadrupole MS

AB Sciex Analyst/Sciex OS

WATSON LIMS

Shimadzu LC systems

Hamilton Starlet robot

Job description

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com . Follow @abbvie on LinkedIn, Facebook , Instagram , X and YouTube.

The candidate for this Senior Scientist position will be working in the Regulated Bioanalysis group in the Quantitative, Translational, and ADME Sciences (QTAS) department. The primary responsibility will be acting as a Principal Investigator to manage projects and studies throughout the bioanalytical lifecycle, which includes but not limited to bioanalytical sample analysis, data review, and report writing for GLP non-clinical and clinical studies. The candidate must be experienced with managing bioanalytical operation workflows in a regulated environment. The individual will also be expected to work cross functionality within QTAS and with Preclinical Safety and clinical Pharmacology.

Key responsibilities

• Overseeing sample analysis of Abbvie assets in support of nonclinical and clinical trials according to regulatory requirements.
• Managing internal and external stakeholders on deliverables and priorities
• Maintain awareness of evolving trends in separations and mass spectrometry
• Maintain and troubleshoot complex LC systems and ultra-sensitive mass spectrometers
• Author and approve method documents for regulated analysis and scientific papers for publication
• Expertise in the cutting-edge assay technologies and excellent assay troubleshooting skills

Qualifications

• Ph.D. with zero years’ experience, M.S. with 8 years, or B.S. with 10+ years of pharma or CRO experience and a degree in Analytical Chemistry or related field required.
• Experience with regulated bioanalysis support in the drug development process.
• Experience with regulatory guidelines for bioanalysis and experienced in this regulated environment (ALCOA principles).
• Experience developing and validating bioanalytical methods for small molecules, large molecules and peptides.
• Experience with operating AB Sciex triple quadrupole mass spectrometers or equivalents (ex: 5500, 6500, 7500).
• Experience with electronic laboratory notebook software, WATSON Laboratory Information Management Software (LIMS), and AB Sciex Analyst/Sciex OS Software.
• Experience with operating Shimadzu Liquid Chromatography instruments or equivalents.
• Experience with Hamilton Starlet automated liquid handling instruments is a plus.
• Strong interpersonal skills, the ability to work independently with minimal supervision in managing multiple projects and priorities and work well within a team, and a desire to learn specific techniques for bioanalysis.

Key Leadership Competencies

• Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance.
• Learns fast, grasps the \"essence\" and can change course quicky where indicated.
• Raises the bar and is never satisfied with the status quo.
• Creates a learning environment, open to suggestions and experimentation for improvement.
• Embraces the ideas of others, nurtures innovation and manages innovation to reality.

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.

We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.

• paid time off (vacation, holidays, sick)
• medical/dental/vision insurance
• 401(k) to eligible employees

This job is eligible to participate in our short-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: https://www.abbvie.com/join-us/reasonable-accommodations.html