Scientist I/II

ABBVIE; North Chicago (IL); On-site; USD 79,000 - 141,000; Full time

Job summary

AbbVie's Quantitative, Translational & ADME Sciences (QTAS) group in North Chicago, IL seeks a Scientist to support high-throughput LC-MS/MS bioanalysis. The role focuses on sample preparation via protein precipitation, LLE, and SPE, plus operation of robotic systems and mass spectrometers.

Independent, detail-oriented scientists will thrive in a fast-paced, collaborative setting. The position offers cross-functional collaboration with Discovery and QTAS, opportunities to mentor junior staff,

Qualifications

• Bachelor’s degree with 5 years of experience in Chemistry or Analytical Chemistry.
• Master’s degree with 2 years of experience in related field.
• Hands-on bioanalysis of small molecules, peptides, and large molecules in pharma.
• Experience with sample preparation and method development.
• Strong interpersonal and independent work skills.

Responsibilities

• Support LC-MS/MS-based PK/PD, efficacy, and exploratory toxicology bioanalytical studies.
• Conduct and optimize sample extraction using protein precipitation, LLE, SPE.
• Operate and troubleshoot robotic systems and LC-MS/MS platforms.
• Troubleshoot pre-analytical and bioanalytical issues.
• Maintain accurate documentation including LIMS and notebooks.
• Collaborate with Discovery and QTAS teams to support bioanalysis.
• Train and mentor junior scientists as needed.

Skills

bioanalysis

LC-MS/MS

sample preparation

protein precipitation

liquid-liquid extraction

solid-phase extraction

robotic systems

LC

data analysis

document control

Education

Bachelor’s degree in Chemistry/Analytical Chemistry

Master’s degree in Chemistry/Analytical Chemistry

Tools

Hamilton

Tecan

Leap/CTC PAL

Agilent HPLCs

Sciex 5500/6500

Discovery Quant

Analyst

SciexOS

MassHunter

LIMS

Job description

• Compensation: USD 78,500 - USD 141,000 - yearly

Company Description

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com . Follow @abbvie on LinkedIn, Facebook , Instagram , X and YouTube.

Job Description

The Quantitative, Translational & ADME Sciences (QTAS) Department at AbbVie, Inc. in North Chicago, IL is seeking aScientist Ito join the Non-Regulated Bioanalysis group. This role supports high-throughput processing of samples from biological matrices and LC-MS/MS-based bioanalysis. The ideal candidate will have experience in bioanalytical sample preparationusinga range of extraction techniques, operational workflows, data analysis, review, and reporting.

This position is well suited for a detail-oriented, motivated scientist who thrives in a fast-paced, collaborative environment and is committed to delivering high-quality results across multiple projects under tight deadlines. The role also involves partnering with cross-functional teams to align bioanalytical processes with scientific and business needs.

Key Responsibilities

Support LC-MS/MS-based PK/PD, efficacy, andexploratory toxicologybioanalytical studies

Conduct andoptimizesample extraction using protein precipitation, liquid/liquid extraction, or solid-phase extraction methods

Operate and troubleshoot robotic systems (Hamilton, Tecan) and LC-MS/MS platforms (Leap/CTC PAL autosamplers, Agilent HPLCs,Sciex5500/6500 triple quadrupole mass spectrometers) and software such as Discovery Quant, Analyst,SciexOS, andMassHunter

Troubleshoot pre-analytical and bioanalytical issues

Maintainaccuratedocumentation of work, including LIMS records, electronic notebooks, test methods, and protocols

Collaborate with teams across Discovery and QTAS to support bioanalysis

Train and mentor junior scientists as needed

Qualifications

Bachelor’s degree with 5 years of experience, orMaster’sdegree with 2 years of experience, in Chemistry, Analytical Chemistry, or a related field

Hands-on experience in bioanalysis of small molecules, peptides, and large molecules in the pharmaceutical industry, including sample preparation and method development

Strong interpersonal skills with the ability to work independently and collaboratively in a high-throughput setting

Experienceoperatingautomated liquid handling robotic platforms such as Hamilton or equaliosystems

Experience operating CTC-PAL and Agilent liquid chromatography instruments, as well as LC-MS/MS platforms such as ABSciextriple quadrupole mass spectrometers or equivalent systems

Experience with electronic laboratory notebook software and Laboratory Information Management Systems (LIMS)

Strong instrument and assay troubleshooting skills

Experience with process development or optimization preferred

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law:

The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this roleat thetimeofthis posting based on the job grade for this position.Individualcompensation paid within this range will depend on manyfactors including geographiclocation,andwemay ultimately pay more or less than the posted range. This range may bemodified in thefuture.

We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.

This job is eligible toparticipate in our short-term incentiveprograms.

Note: No amount of payis considered to bewages or compensation until such amount isearned, vested, anddeterminable.Theamountandavailabilityof anybonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat areallocable to a particular employeeremains in the Company'ssoleandabsolutediscretion unless and until paid andmay bemodified at the Company’s sole and absolutediscretion, consistent withapplicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.