Senior Scientist: High-Throughput Protein Binder Discovery

Initial Therapeutics, Inc.; South San Francisco (CA); On-site; USD 90,000 - 130,000; Full time

Benefits offered by this job

Employee benefits package

Discretionary annual bonus program

Stock-based long-term incentives

Flexible work models

Job summary

Initial Therapeutics, Inc. is seeking a Senior Scientist in South San Francisco to lead efforts in transforming computational protein designs into validated binders and antibodies. Responsibilities include developing high-throughput platforms to generate and validate new binders for target discovery and therapeutic innovation.

The ideal candidate will have a Ph.D. in a related field, extensive protein engineering experience, and the ability to collaborate effectively within cross-functional teams.

Qualifications

• Doctorate degree (PhD or equivalent) or relevant post-doc experience required.
• Experience in expression, purification, and characterization of proteins.
• Strong organizational and communication skills needed.

Responsibilities

• Lead high-throughput workflows for binder expression and characterization.
• Develop strategies for de novo binders and analyze experimental data.
• Collaborate with molecular biology teams for construct generation.

Skills

Protein Engineering

Biochemical characterization

Flow cytometry

High-throughput experimentation

Cellular-based assays

Education

PhD in Biochemistry or related field

Masters with 3 years experience

Bachelors with 5 years experience

Tools

Flow cytometry

SPR (Surface Plasmon Resonance)

Automation platforms

Job description

Initial Therapeutics, Inc. is seeking a Senior Scientist in South San Francisco to lead efforts in transforming computational protein designs into validated binders and antibodies. Responsibilities include developing high-throughput platforms to generate and validate new binders for target discovery and therapeutic innovation.

The ideal candidate will have a Ph.D. in a related field, extensive protein engineering experience, and the ability to collaborate effectively within cross-functional teams.