High-Throughput Discovery Scientist (Direct-to-Biology)

Otsuka Pharmaceutical Co., Ltd; Boston (MA); On-site; USD 124,000 - 178,000; Full time

Benefits offered by this job

Medical coverage

Dental coverage

Vision coverage

Life insurance

Disability insurance

Tuition reimbursement

Student loan assistance

401(k) match

Flexible time off

Paid holidays

Paid leave

Job summary

Jnana Therapeutics, a Boston-based subsidiary of Otsuka, is seeking a Scientist for its Discovery Chemistry team to advance drug discovery with direct-to-biology chemistry and high-throughput screening. You will design, synthesize, and optimize small molecules while collaborating across disciplines to interrogate biology and generate drug candidates for challenging targets.

The role emphasizes pioneering chemistry, automation, and patent-focused output, with a competitive US salary range and

Qualifications

• Ph.D. in Medicinal Chemistry, Organic Chemistry, or closely related field with at least 3 years industry experience in parallel synthesis, liquid handling, high-throughput experimentation and/or direct-to-biology chemistry.
• Passion for drug discovery, highly-organized and excellent communication skills.
• Minimum $123,600.00 - Maximum $177,675.00, plus incentive opportunity: The range shown represents a typical pay range... provided to applicants in accordance with states and local laws.

Responsibilities

• Execute direct-to-biology, high-throughput chemistry to support the platform.
• Develop and optimize new reactions for direct-to-biology chemistry.
• Contribute to establishment of the high-throughput chemistry function and planning/build out of laboratory automation.
• Utilize synthetic expertise to design and execute synthesis of target molecules.
• Work closely with external chemistry CRO teams to synthesize target molecules.
• Work collaboratively across scientific disciplines on multiple projects.
• Proactively engage in brainstorming and the generation of new ideas across projects.
• Assist in preparing patent applications and publications.
• Maintain a safe and productive laboratory environment.

Skills

Parallel synthesis

Liquid handling

High-throughput experimentation

Direct-to-biology chemistry

Drug discovery

Communication skills

Education

Ph.D. in Medicinal Chemistry or Organic Chemistry

Job description

Jnana Therapeutics, a Boston-based subsidiary of Otsuka, is seeking a Scientist for its Discovery Chemistry team to advance drug discovery with direct-to-biology chemistry and high-throughput screening. You will design, synthesize, and optimize small molecules while collaborating across disciplines to interrogate biology and generate drug candidates for challenging targets.

The role emphasizes pioneering chemistry, automation, and patent-focused output, with a competitive US salary range and