Senior Scientist, Gene Regulation for CAR-T Therapies

Johnson & Johnson Co.; Spring House (PA); On-site; USD 140,000 - 190,000; Full time

Job summary

Johnson & Johnson in Spring House, PA seeks a Senior Scientist, Cell Therapy Genetic Regulation to advance CAR T cell programs using cutting-edge gene regulation tools. You will work with human T cells to design, optimize, and deploy genetic regulation strategies across discovery projects.

The role requires deep expertise in genetic engineering, independent lab work, and collaboration with cross-functional teams to drive program milestones and generate impactful data for advancement.

Qualifications

• PhD in Molecular Biology, Bioengineering, Genetics or related field.
• Minimum 2 years of post-PhD biopharmaceutical or biotech experience.
• Strong knowledge in genetic regulation strategies and modulation technologies.
• Experience designing, screening, and validating genetic regulation tools in cell therapy context.
• Ability to independently perform lab-based responsibilities with limited guidance.
• Collaborative skills across teams and effective data exchange.
• Self-motivated, organized, and able to manage competing priorities.

Responsibilities

• Lead development of genetic regulation tools for cell therapy platforms.
• Design, execute, and optimize screening workflows for gene modulation designs.
• Advance assay development and validation for on-target activity and specificity.
• Collaborate with team members and cross-functional groups to hit milestones.
• Stay current with advances in genetic regulation and cell therapy.
• Analyze data, prepare reports, and communicate results to leadership.
• Maintain detailed procedures and ensure lab safety compliance.

Skills

Genetic regulation

Gene modulation

Cell therapy

Lab independence

Cross-functional collaboration

Molecular biology

Data analysis

Education

PhD in Molecular Biology, Bioengineering, Genetics or related

Tools

Flow cytometry

NGS

Molecular cloning

Lentiviral vectors

Viral transduction

Job description

Johnson & Johnson in Spring House, PA seeks a Senior Scientist, Cell Therapy Genetic Regulation to advance CAR T cell programs using cutting-edge gene regulation tools. You will work with human T cells to design, optimize, and deploy genetic regulation strategies across discovery projects.

The role requires deep expertise in genetic engineering, independent lab work, and collaboration with cross-functional teams to drive program milestones and generate impactful data for advancement.