Senior Scientist, Functional Genomics & Target Discovery

BioSpace; South San Francisco (CA); On-site; USD 140,000 - 190,000; Full time

Job summary

Amgen is seeking a Senior Scientist in Target Discovery & Biology (Functional Genomics) in South San Francisco to drive target discovery across therapeutic areas using in vitro to in vivo models. You will apply functional genomics to advance target validation and mechanism-of-action studies in a collaborative, science-driven environment.

You will lead projects from inception through translation, foster cross-site collaboration, and contribute to a pipeline addressing oncology, inflammation, and

Qualifications

• PhD, MD/PharmD or MD/DO required with post‑doc in Target Discovery & Biology.
• Master's degree with 3+ years in Target Discovery & Biology.
• Bachelor's degree with 5+ years in Target Discovery & Biology.

Responsibilities

• Leverage functional genomics across therapeutic areas to discover targets.
• Lead projects from inception to target identification, validation, MOA.
• Foster collaborative, scientifically rigorous team culture to deliver pipeline impact.

Skills

Molecular biology

Cell engineering

CRISPR screens

Data-driven discovery

Cross-site collaboration

Publications track record

Education

PhD

MD/PharmD or MD/DO

Masters in Target Discovery & Biology

Bachelors in Target Discovery & Biology

Job description

Amgen is seeking a Senior Scientist in Target Discovery & Biology (Functional Genomics) in South San Francisco to drive target discovery across therapeutic areas using in vitro to in vivo models. You will apply functional genomics to advance target validation and mechanism-of-action studies in a collaborative, science-driven environment.

You will lead projects from inception through translation, foster cross-site collaboration, and contribute to a pipeline addressing oncology, inflammation, and