Lead Target Discovery Scientist, Functional Genomics

Amgen SA; South San Francisco (CA); Hybrid; USD 120,000 - 190,000; Full time

Benefits offered by this job

Retirement plan

Medical/dental/vision coverage

Stock-based incentives

Generous time-off program

Flexible work options

Job summary

Amgen in South San Francisco is seeking a Senior Scientist in Target Discovery & Biology (Functional Genomics). You will join the Target Discovery & Biology team to advance target discovery across Amgen’s therapeutic areas, applying functional genomics in disease-relevant systems from in vitro to in vivo models.

The role emphasizes leading projects, collaborating cross‑site, and delivering mechanistic insights to reduce disease burden.

Qualifications

• Doctorate degree (PhD) required.
• MD or PharmD alternative with relevant post‑doc experience acceptable.
• Master’s with 3+ years in Target Discovery & Biology.
• Bachelor’s with 5+ years in Target Discovery & Biology.

Responsibilities

• Leverage functional genomics to discover novel targets.
• Lead projects from inception through validation and mechanism studies.
• Foster collaborative, rigorous team culture delivering pipeline impact.

Skills

Functional Genomics

Molecular Biology

Cell Engineering

CRISPR-based screens

Data-driven discovery

Education

PhD

PharmD

MD

Masters + 3 years experience

Bachelor + 5 years experience

Tools

In vitro/in vivo models

Job description

Amgen in South San Francisco is seeking a Senior Scientist in Target Discovery & Biology (Functional Genomics). You will join the Target Discovery & Biology team to advance target discovery across Amgen’s therapeutic areas, applying functional genomics in disease-relevant systems from in vitro to in vivo models.

The role emphasizes leading projects, collaborating cross‑site, and delivering mechanistic insights to reduce disease burden.