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Jacobs Management Group is seeking a Senior Scientist to support biologics manufacturing, process development, and technical operations in Oklahoma City. This hands-on role emphasizes downstream purification, chromatography, UF/DF, and ÄKTA systems with UNICORN software.
You will troubleshoot technical challenges, collaborate cross-functionally with manufacturing, quality, and process development teams, and contribute to process improvements while working primarily onsite with relocation
Senior Scientist, Bioprocessing & Manufacturing Support
Location: Oklahoma City, OK
Compensation: $80,000–$110,000 base salary, with flexibility for exceptional candidates
Work Arrangement: Primarily onsite
Relocation Assistance: Available
We are partnering with an established biopharmaceutical organization seeking an experienced Senior Scientist to support biologics manufacturing, process development, and technical operations.
This opportunity is ideal for a hands‑on scientist with strong downstream purification experience who enjoys solving technical challenges, improving manufacturing processes, and working closely with cross‑functional teams.
The successful candidate will bring practical experience in chromatography, ultrafiltration/diafiltration (UF/DF), and ÄKTA systems with UNICORN software. We are looking for someone who can apply their technical knowledge directly rather than primarily overseeing the work of others.
Provide technical support for downstream biologics manufacturing and process‑related activities.
Apply hands‑on expertise in chromatography, UF/DF, and related purification processes.
Troubleshoot process challenges and support investigations into manufacturing performance.
Collaborate with manufacturing, process development, quality, and other technical groups to address process‑related issues.
Contribute to process improvement, optimization, and technical problem‑solving initiatives.
Support process documentation, technical assessments, and knowledge transfer activities.
Serve as a technical resource while working independently in a collaborative environment.
Bachelor's degree or higher in Biochemistry, Biotechnology, Chemical Engineering, Biology, or a related scientific discipline.
Minimum 5 years of hands‑on experience in downstream process development, MSAT, or biologics manufacturing.
Strong practical knowledge of column chromatography and downstream protein purification.
Experience with ultrafiltration/diafiltration (UF/DF) processes.
Proficiency using ÄKTA chromatography systems and UNICORN software.
Demonstrated ability to troubleshoot technical challenges and explain specific examples of hands‑on process work.
Strong communication, analytical, and cross‑functional collaboration skills.
Experience in a biologics CDMO or commercial biopharmaceutical manufacturing environment.
Exposure to upstream bioprocessing or cell culture operations.
Experience supporting technology transfer, process optimization, or manufacturing scale‑up.
Familiarity with GMP manufacturing environments.
Experience supporting multiple biologics programs or manufacturing processes.
Opportunity to make a meaningful technical contribution in a specialized biologics environment.
Broad exposure to manufacturing operations and cross‑functional technical challenges.
Work closely with experienced scientific and operational leadership.
Competitive benefits and relocation assistance.
An environment that values technical expertise, collaboration, and independent problem‑solving.