Senior Bioprocess Scientist: Downstream MSAT & Purification

Jacobs Management Group; Oklahoma City (OK); On-site; USD 80,000 - 110,000; Full time

Benefits offered by this job

Relocation assistance

Competitive benefits

Job summary

Jacobs Management Group is seeking a Senior Scientist to support biologics manufacturing, process development, and technical operations in Oklahoma City. This hands-on role emphasizes downstream purification, chromatography, UF/DF, and ÄKTA systems with UNICORN software.

You will troubleshoot technical challenges, collaborate cross-functionally with manufacturing, quality, and process development teams, and contribute to process improvements while working primarily onsite with relocation

Qualifications

• Bachelor's degree or higher in Biochemistry, Biotechnology, Chemical Engineering, Biology, or a related scientific discipline.
• Minimum 5 years of hands-on experience in downstream process development, MSAT, or biologics manufacturing.
• Strong practical knowledge of column chromatography and downstream protein purification.
• Experience with ultrafiltration/diafiltration (UF/DF) processes.
• Proficiency using ÄKTA chromatography systems and UNICORN software.
• Demonstrated ability to troubleshoot technical challenges and explain specific examples of hands-on process work.
• Strong communication, analytical, and cross-functional collaboration skills.

Responsibilities

• Provide technical support for downstream biologics manufacturing and process-related activities.
• Apply hands-on expertise in chromatography, UF/DF, and related purification processes.
• Troubleshoot process challenges and support investigations into manufacturing performance.
• Collaborate with manufacturing, process development, quality, and other technical groups to address process-related issues.
• Contribute to process improvement, optimization, and technical problem-solving initiatives.
• Support process documentation, technical assessments, and knowledge transfer activities.
• Serve as a technical resource while working independently in a collaborative environment.

Skills

Downstream purification

Chromatography

UF/DF

Process development

Troubleshooting

Cross-functional collaboration

Technical communication

Education

Bachelor's degree or higher in Biochemistry/ Biotechnology/ Chemical Engineering/ Biology

Tools

ÄKTA systems

UNICORN software

Job description

Jacobs Management Group is seeking a Senior Scientist to support biologics manufacturing, process development, and technical operations in Oklahoma City. This hands-on role emphasizes downstream purification, chromatography, UF/DF, and ÄKTA systems with UNICORN software.

You will troubleshoot technical challenges, collaborate cross-functionally with manufacturing, quality, and process development teams, and contribute to process improvements while working primarily onsite with relocation