Senior Scientist, Antibody Conjugation — Automate & Scale

BioSpace; Brisbane (CA); On-site; USD 175,000 - 185,000; Full time

Benefits offered by this job

Bonus

Equity

Job summary

Nurix is seeking a Senior Scientist, Antibody Conjugation to build and own a new bioconjugation capability. You will develop robust chemistries, transfer workflows to automation, and scale conjugation for in vivo studies.

You will partner with medicinal chemistry, analytical chemistry, computational chemistry, protein biochemistry, and automation teams to move candidates from bench to study-ready material. You will lead method development, protocol transfer to liquid-handling platforms, and

Qualifications

• PhD or equivalent with hands-on bioconjugation experience preferred.
• ,
• ],
• job_responsibilities_description":[

Responsibilities

• Develop and optimize antibody bioconjugation methods for degrading payloads and linkers.

Skills

Antibody bioconjugation chemistry

FPLC/AKTA purification

TFF/SEC/IEX/RP-HPLC/UPLC/HIC/LC-MS DAR

Automation-ready protocols

NHS ester/maleimide coupling

CuAAC/SPAAC/IEDDA

Site-specific conjugation (engineered‑

Unnatural amino acids conjugation

Education

PhD in chemistry/biochemistry/chemical biology or related field

MS/BS with hands-on industry bioconjugation experience

Tools

Hamilton liquid handler

Tecan liquid handling system

Job description

Nurix is seeking a Senior Scientist, Antibody Conjugation to build and own a new bioconjugation capability. You will develop robust chemistries, transfer workflows to automation, and scale conjugation for in vivo studies.

You will partner with medicinal chemistry, analytical chemistry, computational chemistry, protein biochemistry, and automation teams to move candidates from bench to study-ready material. You will lead method development, protocol transfer to liquid-handling platforms, and