Senior Conjugation Scientist

Ultimate Staffing Services; Fenton (MO); On-site; USD 85,000 - 125,000; Full time

Benefits offered by this job

401(k) with company contribution

Paid time off & holidays

Career growth opportunities

Exposure to cutting-edge technologies

Collaborative scientific team

Job summary

Ultimate Staffing Services is seeking a Senior Conjugation Scientist in the St. Louis area to lead development and scale-up of bioconjugation processes for fluorescent, enzymatic, and specialty-labeled proteins.

This role supports new product development and operations in a cutting-edge life sciences environment. The role requires a strong background in protein chemistry, antibody conjugation, and purification techniques, with hands-on experience guiding R&D to production transitions.

Qualifications

• Bachelor's or Master's in Chemistry, Biochemistry, Organic Chemistry, or related field.
• Experience in protein chemistry, antibody conjugation, bioconjugation, or protein labeling.
• Hands-on purification using FPLC, HPLC, SEC, dialysis, and related methods.
• Experience characterizing protein conjugates and analyzing process performance.
• Strong problem-solving, troubleshooting, and analytical skills.
• Ability to work independently while collaborating across multiple teams.

Responsibilities

• Develop, optimize, and scale bioconjugation processes for fluorescent, enzymatic, and specialty-labeled proteins.
• Lead process transfer activities from R&D into manufacturing.
• Optimize reaction conditions, labeling efficiency, yield, stability, and process performance.
• Troubleshoot technical challenges and implement improvements.
• Oversee lab-scale to production-scale conjugation and purification activities.
• Collaborate with analytical, purification, quality, and production teams.
• Present updates and technical findings to leadership.

Skills

Protein chemistry

Bioconjugation

Analytical skills

Independent yet collaborative

Education

Bachelor's or Master's in Chemistry/ Biochemistry/ Organic Chemistry

Tools

FPLC

HPLC

SEC

Dialysis

Job description

Salary: USD85000 - USD125000 per year

Are you ready to drive Innovation in Antibody Conjugation & Bioprocess Development?

We have a great opportunity for you!

• St Louis MO (Onsite)
• Direct Hire | Full-Time Salary: $85,000 - $125,000+ (based on experience and expertise)
• Innovative Life Sciences Environment

Our Life Sciences client is seeking a highly skilled Senior Conjugation Scientist to join our growing New Product Development & Operations team. This is an exciting opportunity for an experienced scientist to play a key role in developing and scaling cutting‑edge bioconjugation processes that support research, diagnostic, and commercial applications worldwide.

If you're passionate about protein chemistry, antibody labeling, process optimization, and translating scientific innovation into scalable production processes, we want to hear from you.

What You'll Do

As a Senior Conjugation Scientist, you'll serve as a technical leader responsible for developing, optimizing, and scaling bioconjugation processes for fluorescent, enzymatic, and specialty‑labeled proteins.

Key responsibilities include:

• Designing and optimizing chemical conjugation processes for antibodies, proteins, and peptides
• Developing robust protocols for fluorophore, enzyme, and specialty-label attachment
• Leading process transfer activities from R&D into manufacturing
• Optimizing reaction conditions, labeling efficiency, yield, stability, and overall process performance
• Troubleshooting technical challenges and implementing process improvements
• Overseeing lab-scale through production-scale conjugation and purification activities
• Collaborating with analytical, cell culture, purification, quality, and production teams
• Managing project timelines and serving as a technical lead for new product initiatives
• Supporting validation activities, process documentation, and compliance with quality systems
• Presenting project updates and technical findings to leadership

Required Qualifications

• Bachelor's or Master's degree in Chemistry, Biochemistry, Organic Chemistry, or a related scientific discipline
• Experience in protein chemistry, antibody conjugation, bioconjugation, or protein labeling
• Hands‑on experience with protein purification techniques such as:
  • FPLC
  • HPLC
  • SEC
  • Dialysis
  • Related purification methodologies
• Experience characterizing protein conjugates and analyzing process performance
• Strong problem‑solving, troubleshooting, and analytical skills
• Ability to work independently while collaborating across multiple teams

Preferred Experience

• Antibody labeling and fluorescent conjugation expertise
• Process scale‑up and technology transfer experience
• Knowledge of chromatography‑based purification processes
• Experience supporting regulated environments, SOPs, and quality systems
• Project leadership and mentoring experience

What We Offer

• Competitive compensation ($85,000 - $125,000+ DOE)
• 401(k) with company contribution
• Paid time off and company holidays
• Career growth opportunities within a thriving biotechnology organization
• Exposure to cutting‑edge scientific technologies and product development
• Collaborative and highly specialized scientific team