Senior Research Associate – Single-Cell Genomics

NewLimit

South San Francisco (CA)

On-site

USD 75,000 - 100,000

Full time

5 days ago
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Benefits offered by this job

401(k) with company match
Health, dental, and vision insurance
Meals and snacks on-site

Job summary

NewLimit is seeking a Senior/Research Associate with experience in biological sample processing and molecular biology to join our Single Cell Technology and Assay Development group. Our team develops and applies advanced molecular and bioanalytical technologies to support therapeutic discovery, spanning single-cell genomics, biomarker development, biodistribution, and bioanalytical method development.

You will design and execute experiments involving isolation, culture, and processing of cells

Qualifications

  • Bachelor's degree in cell biology, molecular biology, or a related natural science or industry experience
  • 2+ years of work experience in a cell or molecular biology laboratory (academic or industry)
  • Experience with standard molecular biology workflows (e.g., nucleic acid extraction, qPCR, ELISA, NGS library construction, library quantification and QC)
  • Experience with necropsy, organ/tissue collection, primary tissue dissociation, mammalian cell culture and sample processing (e.g. single cell suspension preparation, nuclei isolation, fixation)

Responsibilities

  • Measure biodistribution, pharmacokinetics & efficacy of reprogramming medicines using traditional molecular assays and frontier genomics methods
  • Design and execute experiments involving isolation, culture, and processing of cells, tissues, and organs for molecular profiling
  • Collaborate with the Epigenetic Editing team to perform large-scale, single cell perturbation experiments with custom chemistries
  • Perform state-of-the-art single cell profiling experiments to map epigenetic features of age-related disease and evaluate interventions

Skills

Cell culture
Molecular biology workflows
qPCR
ELISA
NGS library construction
Nucleic acid extraction
Nuclei isolation
Single cell suspension
Flow cytometry sorting

Education

Bachelor's degree in cell biology or molecular biology

Tools

10x Genomics
Parse Bio
Perturb-seq / CROProp-seq

Job description

NewLimit is seeking a Senior/Research Associate with experience in biological sample processing and molecular biology to join our Single Cell Technology and Assay Development group. Our team develops and applies advanced molecular and bioanalytical technologies to support therapeutic discovery, spanning single-cell genomics, biomarker development, biodistribution, and bioanalytical method development.

You will design and execute experiments involving isolation, culture, and processing of cells

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