Senior Research Associate – Single-Cell Genomics

NewLimit; South San Francisco (CA); In loco; USD 75.000 - 100.000; Tempo pieno

Vantaggi offerti da questo lavoro

401(k) with company match

Health, dental, and vision insurance

Meals and snacks on-site

Descrizione del lavoro

NewLimit is seeking a Senior/Research Associate with experience in biological sample processing and molecular biology to join our Single Cell Technology and Assay Development group. Our team develops and applies advanced molecular and bioanalytical technologies to support therapeutic discovery, spanning single-cell genomics, biomarker development, biodistribution, and bioanalytical method development.

You will design and execute experiments involving isolation, culture, and processing of cells

Competenze

• Bachelor's degree in cell biology, molecular biology, or a related natural science or industry experience
• 2+ years of work experience in a cell or molecular biology laboratory (academic or industry)
• Experience with standard molecular biology workflows (e.g., nucleic acid extraction, qPCR, ELISA, NGS library construction, library quantification and QC)
• Experience with necropsy, organ/tissue collection, primary tissue dissociation, mammalian cell culture and sample processing (e.g. single cell suspension preparation, nuclei isolation, fixation)

Mansioni

• Measure biodistribution, pharmacokinetics & efficacy of reprogramming medicines using traditional molecular assays and frontier genomics methods
• Design and execute experiments involving isolation, culture, and processing of cells, tissues, and organs for molecular profiling
• Collaborate with the Epigenetic Editing team to perform large-scale, single cell perturbation experiments with custom chemistries
• Perform state-of-the-art single cell profiling experiments to map epigenetic features of age-related disease and evaluate interventions

Conoscenze

Cell culture

Molecular biology workflows

qPCR

ELISA

NGS library construction

Nucleic acid extraction

Nuclei isolation

Single cell suspension

Flow cytometry sorting

Formazione

Bachelor's degree in cell biology or molecular biology

Strumenti

10x Genomics

Parse Bio

Perturb-seq / CROProp-seq

Descrizione del lavoro

NewLimit is seeking a Senior/Research Associate with experience in biological sample processing and molecular biology to join our Single Cell Technology and Assay Development group. Our team develops and applies advanced molecular and bioanalytical technologies to support therapeutic discovery, spanning single-cell genomics, biomarker development, biodistribution, and bioanalytical method development.

You will design and execute experiments involving isolation, culture, and processing of cells