Senior Research Associate - High-Throughput Protein Binder

SLAS (Society for Laboratory Automation and Screening); Watertown (MA); On-site; USD 90,000 - 130,000; Full time

Benefits offered by this job

Competitive compensation

Equity

Benefits

Job summary

Digital Biology is seeking a Senior Research Associate to execute and scale high-throughput protein binder screening campaigns, generating large, information-rich datasets for AI protein-design models.

You will run end-to-end assays, manage multiple external-partner campaigns, and collaborate with protein engineers, automation and computational scientists to improve throughput, accuracy and reproducibility.

Qualifications

• BS, MS, or equivalent experience in protein biochemistry, molecular biology, biological engineering, or a related field.
• Industry experience with high-throughput assays and strong molecular biology fundamentals.
• Demonstrated ability to execute and troubleshoot complex, multi-step workflows.
• Experience with or strong interest in laboratory automation.

Responsibilities

• Execute end-to-end, high-throughput display campaigns, including library preparation, production, selection, amplification, and sequencing preparation.
• Manage concurrent partner campaigns against defined timelines, quality standards, and deliverables.
• Optimize key steps within complex workflows and improve throughput, reproducibility, cost, and turnaround time.
• Maintain rigorous documentation, sample traceability, and standardized procedures.
• Collaborate with computational teams to structure experimental data and metadata for downstream analysis.
• Partner with automation engineers to optimize robotic liquid-handling workflows.
• Communicate campaign progress, results, risks, and recommendations to stakeholders.

Skills

High-throughput screening

Troubleshooting workflows

Collaborative communication

Education

BS/MS or equivalent in protein biochemistry or molecular biology

Tools

Laboratory automation

Job description

Digital Biology is seeking a Senior Research Associate to execute and scale high-throughput protein binder screening campaigns, generating large, information-rich datasets for AI protein-design models.

You will run end-to-end assays, manage multiple external-partner campaigns, and collaborate with protein engineers, automation and computational scientists to improve throughput, accuracy and reproducibility.