Senior Research Associate

Advanced Clinical; Cambridge (MA); On-site; USD 85,000 - 130,000; Full time

Benefits offered by this job

Health coverage

Life insurance

Disability insurance

401k benefits

Job summary

Advanced Group in Cambridge, MA is seeking a Senior Research Associate to support transcriptomics research through NGS workflows and related sample processing. You will ensure high-quality data generation, operational excellence, and continuous improvement while collaborating with a multidisciplinary team.

The role emphasizes hands-on sequencing, library prep, QC, and data reporting, with opportunities to train staff and advance technologies in a fast-paced lab setting.

Qualifications

• Bachelor's or Master's degree in Molecular Biology, Genetics, Genomics, Biology, or related field.
• Hands-on experience with NGS workflows including RNA isolation, library preparation, sequencing, and QC.
• Experience supporting transcriptomics or genomics research programs.
• Strong lab troubleshooting, organization, and documentation skills.
• Experience maintaining accurate sample records and laboratory data.
• Strong written and verbal communication skills.
• Ability to manage multiple priorities in a fast-paced environment.

Responsibilities

• Support transcriptomics studies using bulk RNA sequencing, small RNA sequencing, long-read sequencing, single-cell, spatial methodologies.
• Perform RNA isolation, library preparation, QC, sequencing, and related sample processing activities.
• Operate, maintain, and troubleshoot NGS instrumentation and lab equipment.
• Manage sample tracking, logistics, and data collection workflows.
• Prepare protocols, technical documentation, and data reports.
• Support development and optimization of new technologies and workflows.
• Troubleshoot issues and contribute to process improvements.
• Train and assist laboratory personnel as needed.
• Adapt to evolving project priorities and platform needs.

Skills

RNA sequencing workflows

RNA isolation

Library preparation

Quality control

Troubleshooting

Sample tracking

Documentation

Data collection

Communication

Education

Bachelor's or Master's in Molecular Biology/Genomics

Tools

NGS instrumentation

Job description

We are seeking a Senior Research Associate to support transcriptomics research through the execution of next-generation sequencing (NGS) workflows and related sample processing activities. This role will support a variety of sequencing-based applications while ensuring high-quality data generation, operational excellence, and continuous process improvement.

Key Responsibilities

• Support transcriptomics studies using bulk RNA sequencing, small RNA sequencing, long-read sequencing, single-cell, spatial, and related genomics platforms.
• Perform RNA isolation, library preparation, quality control, sequencing, and associated sample processing activities.
• Operate, maintain, and troubleshoot NGS instrumentation and laboratory equipment.
• Manage sample tracking, logistics, and data collection workflows.
• Prepare protocols, technical documentation, and data reports.
• Support development, optimization, and implementation of new technologies and laboratory workflows.
• Troubleshoot technical issues and contribute to process improvement initiatives.
• Train and assist laboratory personnel as needed.
• Adapt to evolving project priorities, workflows, and platform needs.

Required Qualifications

• Bachelor's or Master's degree in Molecular Biology, Genetics, Genomics, Biology, or a related scientific discipline.
• Hands-on experience with NGS workflows, including RNA isolation, library preparation, sequencing, and quality control.
• Experience supporting transcriptomics or genomics research programs.
• Strong laboratory troubleshooting, organization, and documentation skills.
• Experience maintaining accurate sample records and managing laboratory data.
• Strong written and verbal communication skills.
• Ability to manage multiple priorities in a fast-paced research environment.

Preferred Qualifications

• Experience with bulk RNA-seq, small RNA-seq, long-read sequencing, single-cell sequencing, spatial transcriptomics, or related technologies.
• Experience operating and maintaining NGS instrumentation.
• Experience developing or optimizing laboratory workflows and protocols.
• Experience training or mentoring laboratory staff.
• Experience working in biotechnology, pharmaceutical, academic, or other research environments.

Full-time employees are also eligible for benefits options such as health coverage, life insurance, disability insurance, and 401k benefits.

At Advanced Group, our commitment to diversity and inclusion in every part of our organization is crucial to fulfilling our mission and demonstrating our REAL values. Advanced Group is committed to providing employment opportunities without regard to sex, race, color, age, national origin, religion, gender identity or expression, sexual orientation or sexual preference, pregnancy or maternity, genetic information, marital status, disability, veteran status, or any other basis protected by applicable federal, state or local law.

Advanced Group complies with federal and state disability laws and makes reasonable accommodations for applicants and candidates with disabilities. If a reasonable accommodation is needed to participate in the job application or interview process, please contact [e-mail].