Associate NGS Scientist

Legend Biotech; Possumtown (NJ); On-site; USD 70,000 - 90,000; Full time

Job summary

Legend Biotech is seeking an Associate NGS Scientist to join their R&D team in New Jersey. This role involves implementing new next-generation sequencing assays and conducting DNA and RNA extraction of biological samples. The successful candidate will have a strong background in molecular biology and hands-on experience with NGS library preparation.

With a commitment to quality and a focus on collaborative troubleshooting, this position is perfect for enthusiastic scientists eager to contribute to groundbreaking advances in CAR‑T cell therapy.

Qualifications

• Proficiency with basic molecular biology techniques, DNA and RNA quantification technologies, PCR, and qPCR required.
• 1 year direct hands-on experience with NGS library preparation and sequencing run set up preferred.
• Experience working in a regulated environment under a controlled design review process preferred.

Responsibilities

• DNA and RNA extraction of biological samples.
• Library preparation for next generation sequencing.
• Develop and execute various QC methodologies to assess quality of samples.
• Maintain detailed laboratory notes on experiments.
• Perform other lab experiments as planned and document all observations.
• Participate with R&D team in troubleshooting and optimization.

Skills

Molecular biology techniques

DNA and RNA quantification technologies

PCR

qPCR

Illumina NGS workflow

Organizational skills

Communication skills

Education

M.S or Ph.D in relevant field

Job description

From the very beginning, we have been focusing on the science. We came together as a team of experts, committed to quality, driven by excellence, and dedicated to experimentation. Though we faced many challenges, we remained fearless in our research and rigorous in our thinking, pushing ourselves to work harder. However, what affected us the most was the enormous burden patients bear and the difficulties they face, which drove us to think about what’s next.

We believe it is time to accelerate and expand that transformation. At Legend Biotech, we are excited to bring clinical trials to patients in our pursuit of a cure. While we are focusing on CAR‑T in multiple myeloma, we firmly believe the prospects of cellular therapy stretch beyond just one disease or indication. The spark of hope is lit. At Legend Biotech, we are using that hope to ignite the future of CAR‑T cell therapy.

Job Description

Role Overview:

As an Associate NGS Scientist in the R&D team, you will contribute to the development of cutting‑edge solutions for Next Generation Sequencing. This individual will be charged with implementing new next‑generation sequencing assays as well as running existing validated assays and sequencers while following established policies and procedures in a professional manner. Successful candidate must be passionate about wet‑lab driven experimentation and a team player.

Major Responsibilities:

• DNA and RNA extraction of biological samples.
• Library preparation for next generation sequencing.
• Develop and execute various QC methodologies to assess quality of samples, running NGS sequencer.
• Maintain detailed laboratory notes on experiments, generate reports summarizing experimental results and communicate them to project teams.
• Perform other lab experiments as planned and document all observations and findings.
• Participate with other R&D team members in troubleshooting and identifying new opportunities for optimization and applications.

Qualifications

Education: M.S or Ph.D preferred

Experience:

• Proficiency with basic molecular biology techniques, DNA and RNA quantification technologies, PCR, and qPCR is required.
• 1 year direct hands‑on experience with NGS library preparation and sequencing run set up is preferred.
• Illumina NGS workflow and platform experience.

Key Capabilities, Knowledge, and Skills:

• Able to multi‑task effectively and be fully committed to project timelines.
• Strong organization and communication skills.
• Able to work in a fast‑pace environment.
• Experience working in a regulated environment under a controlled design review process is preferred.

Additional Information

Legend Biotech USA Inc. is a proud equal opportunity/affirmative action employer committed to attracting, retaining, and maximizing the performance of a diverse and inclusive workforce. It is Legend’s policy to ensure equal employment opportunity without discrimination or harassment based on race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, age, disability, national origin, marital or domestic/civil partnership status, genetic information, citizenship status, uniformed service member or veteran status, or any other characteristic protected by law.