Senior Quantitative Biomarker Scientist

Regeneron Pharmaceuticals, Inc.; Village of Tarrytown (NY); Presencial; USD 110 000 - 160 000; Tempo integral

Resumo da oferta

Regeneron Pharmaceuticals, Inc. is seeking a highly qualified data scientist to join the Precision Medicine Quantitative Translational Sciences (PMQTS) team in Tarrytown/Armonk, NY.

The role focuses on exploratory analyses of omics, EHR, wearable, imaging, and other biomarker data, plus development of tools and dashboards for data processing and visualization. The candidate will work on data integration, statistical modeling, and collaborates withClinical Development to translate findings into

Qualificações

• PhD or MS with minimum 2 years in a quantitative field.
• Experience with statistical modeling, ML, and data blending.
• Proficiency in R, Python, or MATLAB; Linux/cloud environment.
• Knowledge of data mapping for systems integration and data provisioning.

Responsabilidades

• Collaborate to analyze biomarker data types across Precision Medicine and biomarker studies.
• Provide computational and technical expertise on data cleaning and data visualization.
• Integrate complex datasets to perform statistical analysis on exploratory biomarker data and clinical endpoints.
• Follow data quality concepts and best practices; perform root cause analysis on data quality issues.
• Prepare scientific presentations, manuscripts, and quality-checked tables/graphs.

Conhecimentos

Statistical modeling

Machine learning

Data visualization

Scripting (R/Python)

Formação académica

PhD or Master’s with relevant experience

Ferramentas

R

Python

MATLAB

Linux

Cloud

Descrição da oferta de emprego

Regeneron is advancing its pipeline portfolio using a data-driven human translational approach. As part of this initiative, the Precision Medicine team is integrated with Discovery Research and Clinical Development teams to promote early adoption of biomarker strategy to guide clinical translation. The team collaborates with Clinical Sciences colleagues to develop the clinical experimental sciences (CES) studies for generating clinically testable, mechanistic hypotheses for each molecule, including developing scientific rationale for initial and new indications for PoC. Precision Medicine leads the biomarker strategy and execution, to achieve proof of mechanism/concept in early clinical trials. The team also implements Precision Medicine strategies, including patient stratification and selection, to support late-stage clinical programs and companion diagnostics.

This is a statistical computational role that falls within Precision Medicine Quantitative Translational Sciences (PMQTS), the analytical arm of Precision Medicine. We are looking for a motivated individual who can conduct clinical trial data management and data analysis in an open and collaborative working environment. This role will encompass exploratory analyses and visualization of omics, EHR, wearable sensor, imaging, and other biomarker data. This position is also involved in the development of tools and dashboards for processing, analyzing, querying, visualizing, and cleaning data.

#PMQBS

When & where:

Work Location: Tarrytown, NY or Armonk, NY

Work model/flexibility: 4 days per week on site

Discover your role:

• Liaise with Precision Medicine Quantitative Translational Sciences to analyze biomarker data types across a range of Precision Medicine and biomarker studies.
• Provide computational and technical expertise on data cleaning and data visualization.
• Integrate complex datasets to perform statistical analysis on exploratory biomarker data and clinical endpoints. Use technical tools, language, or custom coding and systems analysis to clean data and select or create datasets for analysis.
• Understand and follow data quality concepts and best practices and tools. Identify data anomalies and work with data stewards in other units to perform root cause analysis on data quality issues.
• Assist in the preparation of scientific presentations, manuscripts, and reports, including the preparation of quality checked tables and graphs depicting research results.
• Effectively communicate analytical plans and timelines for multiple concurrent projects with study team members.
• Develop, benchmark, and implement new computational workflows as necessary
• Maintain best coding and data cataloguing practices for business consistency and scientific reproducibility.

This role requires:

• PhD, or Masters with minimum 2 years of relevant work experience in one of the following or otherwise related quantitative fields: Computer Science, Computational Biology, Systems Biology, Quantitative Biology, Bioinformatics, Data Analytics, Statistics, Biostatistics, Mathematics, Applied Mathematics, Physics, Chemistry.
• You have experience with statistical modeling/regression, machine learning, and other relevant data blending abilities.
• You have experience in at least one of the following scripting languages: R, Python, MATLAB. Other languages such as SQL, Spark, and C++ are a bonus.
• You have experience working in a Linux and/or cloud, shell scripting, and notebook environment.
• You have knowledge of structured data, with the ability to perform data mapping for systems integration, data provisioning, and data consumption (strongly preferred).
• You have a working knowledge of clinical trials (strongly preferred.)

Equal Opportunity and Inclusion Statement

We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Salary and benefits

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of