Senior Quantitative Biomarker Scientist

Regeneron Pharmaceuticals, Inc (USA); Village of Tarrytown (NY); On-site; USD 110,000 - 179,000; Full time

Job summary

Regeneron Pharmaceuticals, Inc (USA) seeks a data-driven quantitative translational scientist to advance precision medicine studies. The role focuses on clinical trial data management, biomarker data analyses, and the development of tools to process, query, visualize, and clean diverse data types.

Work will be conducted on-site in Tarrytown or Armonk, NY, four days per week, contributing to biomarker strategy and exploratory analyses across multiple studies with cross-functional teams.

Qualifications

• PhD or MSc in a quantitative field with 2+ years relevant work experience.
• Experience with statistical modeling, regression, and ML.
• Proficiency in R, Python, and/or MATLAB; SQL/Spark/C/C++ a bonus.
• Experience with Linux, cloud environments, shell scripting, and notebooks.
• Knowledge of structured data mapping for system integration.
• Working knowledge of clinical trials preferred.

Responsibilities

• Analyze biomarker data across PMQTS studies and related programs.
• Provide data cleaning, processing, and visualization support.
• Integrate complex datasets for statistical analyses of exploratory biomarker data.
• Develop workflows to select or create datasets for analysis.
• Prepare quality tables and graphs for presentations and reports.
• Communicate analysis plans and timelines across multiple projects.

Skills

PhD/Masters in quantitative field

Statistical modeling & ML

R/Python/MATLAB

Linux/Cloud scripting

Structured data mapping

Clinical trials knowledge

Education

PhD or MSc in quantitative field

Tools

R

Python

MATLAB

Job description

Regeneron is advancing its pipeline portfolio using a data-driven human translational approach. As part of this initiative, the Precision Medicine team is integrated with Discovery Research and Clinical Development teams to promote early adoption of biomarker strategy to guide clinical translation. The team collaborates with Clinical Sciences colleagues to develop the clinical experimental sciences (CES) studies for generating clinically testable, mechanistic hypotheses for each molecule, including developing scientific rationale for initial and new indications for PoC. Precision Medicine leads the biomarker strategy and execution, to achieve proof of mechanism/concept in early clinical trials. The team also implements Precision Medicine strategies, including patient stratification and selection, to support late-stage clinical programs and companion diagnostics. This is a statistical computational role that falls within Precision Medicine Quantitative Translational Sciences (PMQTS), the analytical arm of Precision Medicine. We are looking for a motivated individual who can conduct clinical trial data management and data analysis in an open and collaborative working environment. This role will encompass exploratory analyses and visualization of omics, EHR, wearable sensor, imaging, and other biomarker data. This position is also involved in the development of tools and dashboards for processing, analyzing, querying, visualizing, and cleaning data.

When & where:

Work Location: Tarrytown, NY or Armonk, NY Work model/flexibility: : 4 days per week on site

Discover your role:

• Liaise with Precision Medicine Quantitative Translational Sciences to analyze biomarker data types across a range of Precision Medicine and biomarker studies.
• Provide computational and technical expertise on data cleaning and data visualization.
• Integrate complex datasets to perform statistical analysis on exploratory biomarker data and clinical endpoints.
• Use technical tools, language, or custom coding and systems analysis to clean data and select or create datasets for analysis.
• Understand and follow data quality concepts and best practices and tools.
• Identify data anomalies and work with data stewards in other units to perform root cause analysis on data quality issues.
• Assist in the preparation of scientific presentations, manuscripts, and reports, including the preparation of quality checked tables and graphs depicting research results.
• Effectively communicate analytical plans and timelines for multiple concurrent projects with study team members.
• Develop, benchmark, and implement new computational workflows as necessary.
• Maintain best coding and data cataloguing practices for business consistency and scientific reproducibility.

This role requires:

• PhD, or Masters with minimum 2 years of relevant work experience in one of the following or otherwise related quantitative fields: Computer Science, Computational Biology, Systems Biology, Quantitative Biology, Bioinformatics, Data Analytics, Statistics, Biostatistics, Mathematics, Applied Mathematics, Physics, Chemistry.
• You have experience with statistical modeling/regression, machine learning, and other relevant data blending abilities.
• You have experience in at least one of the following scripting languages: R, Python, MATLAB. Other languages such as SQL, Spark, and C++ are a bonus.
• You have experience working in a Linux and/or cloud, shell scripting, and notebook environment.
• You have knowledge of structured data, with the ability to perform data mapping for systems integration, data provisioning, and data consumption (strongly preferred).
• You have a working knowledge of clinical trials (strongly preferred).
• #PMQBS

Does this sound like you?

We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law.

Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Salary Range (annually) $109,900.00 - $179,300.00

Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role:

• annual bonuses or other incentive plans
• equity awards
• pension or retirement benefits
• 401(k) company match
• health and wellness programs
• fitness centers
• insurance benefits (e.g. medical, dental, vision, life and disability)
• paid time off
• family support benefits

For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process.

Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on-site.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based.

The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.

Regeneron is a leading biotechnology company that invents life-transforming medicines for people with serious diseases. Founded and led for over 30 years by physician-scientists, our unique ability to repeatedly and consistently translate science into medicine has led to nine FDA-approved treatments and numerous product candidates in development, almost all of which were homegrown in our laboratories. Our medicines and pipeline are designed to help patients with eye diseases, allergic and inflammatory diseases, cancer, cardiovascular and metabolic diseases, neurology, infectious diseases and rare diseases. Regeneron is also proud of award winning culture of innovation, being recognized as a Great Place to Work in 2021, Fast Company’s Best Workplace for Innovators in 2020, and Forbes JUST companies in 2020, among others.