Senior Principal Statistical Programmer - Remote SAS/R Leader

WCG Clinical, Inc.; Carson City (NV); Remote; USD 131,000 - 160,000; Full time

Job summary

WCG Clinical, Inc. is seeking a Senior Principal Statistical Programmer to lead complex programming initiatives for clinical trials and DMC deliverables. You will provide expert guidance, drive standards, and oversee SAS-based outputs across studies.

You will mentor staff, collaborate with biostatistics, data management, and IT teams, and ensure regulatory compliance and CDISC alignment. This remote US-based role supports multiple trials and seeks a strategic, technically rigorous leader.

Qualifications

• Master's degree required. In limited circumstances, an equivalent combination of education and directly relevant professional experience may be considered.
• 8–10 years of statistical programming experience in a clinical trial environment.
• Deep expertise in SAS programming, including complex analyses and regulatory deliverables.
• Proficiency in R programming.
• Demonstrated experience with CDISC standards and regulatory requirements.
• Proven ability to independently lead complex programming efforts across studies.
• Experience mentoring staff and driving technical standards or best practices.

Responsibilities

• Design, develop, validate, and oversee complex statistical programming deliverables, including analysis datasets, tables, listings, and figures.
• Lead the development, validation, and continuous improvement of DMC macros and programming standards.
• Provide technical oversight and review of programming work to ensure quality, compliance, and consistency across deliverables.
• Drive the establishment and adoption of programming standards, best practices, and process improvements.
• Collaborate with biostatistics and study teams to support complex trial designs, analyses, and DMC reporting.
• Independently manage and prioritize programming activities across multiple studies or initiatives.
• Mentor and provide technical leadership to statistical programming staff, supporting skill development and best practices.
• Contribute technical expertise to proposals, project planning, and scope discussions as needed.
• Partner with IT and technology teams to support SAS environments, tools, and system validation efforts.
• Provide technical oversight for programming activities supporting regulatory submissions and inspection readiness.
• Ensure programming deliverables align with regulatory expectations, submission requirements, and CDISC standards.
• Influence programming approaches, standards, and best practices across multiple studies or programs.

Skills

SAS programming

R programming

CDISC standards

Leadership

Mentoring

Education

Master's degree

Tools

SAS environments

Job description

WCG Clinical, Inc. is seeking a Senior Principal Statistical Programmer to lead complex programming initiatives for clinical trials and DMC deliverables. You will provide expert guidance, drive standards, and oversee SAS-based outputs across studies.

You will mentor staff, collaborate with biostatistics, data management, and IT teams, and ensure regulatory compliance and CDISC alignment. This remote US-based role supports multiple trials and seeks a strategic, technically rigorous leader.