Senior Principal Statistical Programmer - Lead & Innovate

WCG; United States; On-site; USD 131,000 - 160,000; Full time

Benefits offered by this job

Health, dental, vision, life and 
dis&

401(k) with company match

Flexible spending accounts

Tuition reimbursement

On-the-job training and certification

Paid holidays, vacation, and sick time

Job summary

WCG is seeking a Senior Principal Statistical Programmer in the United States to lead advanced statistical programming for clinical trials. You will design, validate, and standardize outputs like tables, listings, and figures while driving quality, compliance, and efficiency across projects.

You will mentor staff, influence programming standards, and collaborate with biostatistics, data management, and IT teams to support regulatory submissions and CDISC adherence.

Qualifications

• Minimum 8–10 years of statistical programming experience in a clinical trial environment.
• Deep expertise in SAS programming, including complex analyses and regulatory deliverables.
• Proficiency in R programming.
• Demonstrated experience with CDISC standards and regulatory requirements.
• Proven ability to lead complex programming efforts across studies.
• Experience mentoring staff and driving technical standards or best practices.

Responsibilities

• Serve as a senior technical expert in statistical programming across multiple studies or functional areas.
• Design, develop, validate, and oversee complex programming deliverables, including analysis datasets, tables, listings, and figures.
• Lead the development, validation, and continuous improvement of DMC macros and programming standards.
• Provide technical oversight and review of programming work to ensure quality, compliance, and consistency.
• Drive programming standards, best practices, and process improvements.
• Collaborate with biostatistics and study teams to support complex trial designs, analyses, and DMC reporting.
• Independently manage and prioritize programming activities across multiple studies or initiatives.
• Mentor and provide technical leadership to programming staff.

Skills

Technical leadership

Mentoring

Project management

Independent problem solving

Education

Master’s degree in statistics/biostatistics or related

Tools

SAS

R

CDISC standards

Job description

WCG is seeking a Senior Principal Statistical Programmer in the United States to lead advanced statistical programming for clinical trials. You will design, validate, and standardize outputs like tables, listings, and figures while driving quality, compliance, and efficiency across projects.

You will mentor staff, influence programming standards, and collaborate with biostatistics, data management, and IT teams to support regulatory submissions and CDISC adherence.