Senior Peptide Chemist (SPPS) - Hands-On, Clinic-Ready

Discover International; Cape Coral (FL); In loco; USD 85.000 - 115.000; Tempo pieno

Descrizione del lavoro

Discover International is partnering with a clinical-stage oncology biotech to hire a hands-on peptide chemist who thrives at the bench and can deliver difficult sequences independently. The role centers on day-to-day SPPS, peptide purification, and analytical validation, with close collaboration to a senior peptide lead on programs advancing toward the clinic.

Strong SPPS and HPLC skills are essential; GMP experience is a plus for this position based in the US.

Competenze

• Substantial hands-on SPPS experience (automated synthesizers; CEM Liberty Blue is a plus)
• Strong prep and analytical HPLC skills
• GMP experience is a plus

Mansioni

• Run SPPS day to day, including short, cyclic and modified peptides with unnatural amino acids
• Troubleshoot couplings, cleavage and cyclization
• Purify your own peptides by prep HPLC and check them by analytical HPLC and LC-MS
• Work closely with a senior peptide lead on programs heading towards the clinic

Conoscenze

SPPS experience

HPLC skills

GMP awareness

Troubleshooting

Strumenti

Automated synthesizers

CEM Liberty Blue

Descrizione del lavoro

Discover International is partnering with a clinical-stage oncology biotech to hire a hands-on peptide chemist who thrives at the bench and can deliver difficult sequences independently. The role centers on day-to-day SPPS, peptide purification, and analytical validation, with close collaboration to a senior peptide lead on programs advancing toward the clinic.

Strong SPPS and HPLC skills are essential; GMP experience is a plus for this position based in the US.