Senior Microfluidics & Consumables Engineer (End-to-End)

System One; Cambridge (MA); On-site; USD 88,000 - 120,000; Full time

Job summary

System One is seeking a Microfluidics / Consumable Engineer for a contract-to-hire role in Boston, MA. You will own the engineering of consumables for the manufacturing platform and drive end-to-end flow path design, materials selection, and fabrication processes.

The role requires 6+ years in microfluidics device development, an advanced engineering degree, and hands-on fabrication experience. Onsite work during standard hours with competitive compensation.

Qualifications

• MS or PhD in mechanical, chemical, or biomedical engineering, or a related discipline with a microfluidics specialization.
• Six years of experience designing and building microfluidic devices in real use.
• Strong understanding of low-Reynolds-number flow, mixing, pressure drop, residence time, and nanoparticle formation.
• Hands-on fabrication across two or more processes (injection molding, hot embossing, laser micromachining, CNC micro-milling, film lamination, welding, or bonding).
• Experience in fluidic network design or CFD applied to real design decisions.

Responsibilities

• Own the engineering of the consumables for the manufacturing platform.
• Manage end-to-end process flow paths including DNA template prep/amplification, purification/filtration, encapsulation.
• Design channel geometry and hydrodynamics, mixing elements, valve and actuator placement, sensing locations, interfaces.
• Select materials and joining methods compatible with ISO 11137 sterilization.
• Conduct bench de-risking of cartridge unit operations and verify cartridges against acceptance criteria.

Skills

Microfluidics

Particle size control

Fluid dynamics

Experimental design

Team collaboration

Education

MS or PhD in mechanical, chemical, or biomedical engineering (microfluidics specialization)

Tools

CFD

Injection molding

Laser micromachining

CNC micro-milling

Job description

System One is seeking a Microfluidics / Consumable Engineer for a contract-to-hire role in Boston, MA. You will own the engineering of consumables for the manufacturing platform and drive end-to-end flow path design, materials selection, and fabrication processes.

The role requires 6+ years in microfluidics device development, an advanced engineering degree, and hands-on fabrication experience. Onsite work during standard hours with competitive compensation.