Microfluidics / Consumable Engineer

System One; Cambridge (MA); On-site; USD 88,000 - 120,000; Full time

Job summary

System One is seeking a Microfluidics / Consumable Engineer for a contract-to-hire role in Boston, MA. You will own the engineering of consumables for the manufacturing platform and drive end-to-end flow path design, materials selection, and fabrication processes.

The role requires 6+ years in microfluidics device development, an advanced engineering degree, and hands-on fabrication experience. Onsite work during standard hours with competitive compensation.

Qualifications

• MS or PhD in mechanical, chemical, or biomedical engineering, or a related discipline with a microfluidics specialization.
• Six years of experience designing and building microfluidic devices in real use.
• Strong understanding of low-Reynolds-number flow, mixing, pressure drop, residence time, and nanoparticle formation.
• Hands-on fabrication across two or more processes (injection molding, hot embossing, laser micromachining, CNC micro-milling, film lamination, welding, or bonding).
• Experience in fluidic network design or CFD applied to real design decisions.

Responsibilities

• Own the engineering of the consumables for the manufacturing platform.
• Manage end-to-end process flow paths including DNA template prep/amplification, purification/filtration, encapsulation.
• Design channel geometry and hydrodynamics, mixing elements, valve and actuator placement, sensing locations, interfaces.
• Select materials and joining methods compatible with ISO 11137 sterilization.
• Conduct bench de-risking of cartridge unit operations and verify cartridges against acceptance criteria.

Skills

Microfluidics

Particle size control

Fluid dynamics

Experimental design

Team collaboration

Education

MS or PhD in mechanical, chemical, or biomedical engineering (microfluidics specialization)

Tools

CFD

Injection molding

Laser micromachining

CNC micro-milling

Job description

Job Title: Microfluidics / Consumable Engineer
Location: Boston, MA
Type: Contract to Hire
Compensation: $75.96
Work Model: Onsite – onsite
Hours: Standard business hours
Security Clearance: Not specified

Overview
Join a growing biotechnology organization in the U.S. that focuses on next-generation RNA medicine manufacturing. The Microfluidics/Consumable Engineer will be responsible for the engineering of the consumables for the manufacturing platform.

Responsibilities

• Own the engineering of the consumables for the manufacturing platform.
• Manage the flow path carrying every unit operation of the end-to-end process including DNA template preparation/amplification, purification/filtration, and encapsulation.
• Design channel geometry and hydrodynamics, mixing elements, valve and actuator placement, in-line sensing locations, and fluid-path interfaces to various subsystems.
• Select materials and joining methods compatible with sterilization under ISO 11137.
• Conduct bench de-risking of cartridge unit operations, fabricate the initial cartridge lot, and verify cartridges against set acceptance criteria.

Requirements

• MS or PhD in mechanical, chemical, or biomedical engineering, or a related discipline with a microfluidics specialization.
• At least six years of experience designing and building microfluidic or milli-fluidic devices that have gone into real use.
• Strong understanding of low-Reynolds-number flow, mixing, pressure drop, residence time, and microfluidic nanoparticle formation, including how mixing parameters impact particle size, polydispersity, and encapsulation efficiency.
• Hands‑on fabrication experience across at least two of the following: injection molding, hot embossing, laser micromachining, CNC micro‑milling, film lamination, laser or ultrasonic welding, and pressure‑sensitive adhesive bonding.
• Experience in fluidic network design and/or CFD applied to real design decisions.

System One, and its subsidiaries including Joulé and Mountain Ltd., are leaders in delivering outsourced services and workforce solutions across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan.

System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.

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