Senior Medical Director, Clinical Development

City Therapeutics; Cambridge (MA); On-site; USD 255,000 - 290,000; Full time

Job summary

City Therapeutics seeks a Senior Director, Clinical Development (Medical Director) to provide medical leadership across clinical programs in Cambridge, MA. The role leads clinical strategy, protocol development, study execution, data interpretation, and regulatory interactions, collaborating with operations, biometrics, pharmacology, toxicology, and regulatory teams.

This is a physician-scientist role driving programs from early development toward milestones and approvals.

Qualifications

• MD or equivalent medical degree required.
• Board certification or board eligibility in a relevant medical specialty strongly preferred.
• 6+ years of relevant clinical development experience within the biotechnology or pharmaceutical industry.
• Experience serving as a medical monitor and providing medical leadership for clinical trials.
• Demonstrated experience designing and executing early-stage clinical studies; experience supporting programs through later-stage development is highly desirable.

Responsibilities

• Provide medical and scientific leadership for one or more clinical development programs.
• Develop and execute clinical development plans aligned with program objectives.
• Lead the design of clinical study protocols, endpoints, eligibility criteria, dose-escalation strategies, and safety plans.
• Serve as medical monitor and oversight of participant safety and data.
• Collaborate with Clinical Operations to ensure high-quality study execution.
• Review and interpret safety, efficacy, PK/PD, and biomarker data.

Skills

Leadership

Clinical trial design

Regulatory knowledge

Cross-functional collaboration

Communication

Education

MD or equivalent medical degree

Job description

City Therapeutics seeks a Senior Director, Clinical Development (Medical Director) to provide medical leadership across clinical programs in Cambridge, MA. The role leads clinical strategy, protocol development, study execution, data interpretation, and regulatory interactions, collaborating with operations, biometrics, pharmacology, toxicology, and regulatory teams.

This is a physician-scientist role driving programs from early development toward milestones and approvals.