Senior Manufacturing Systems Engineer, Pharma Automation Leader

Amgen SA; Holly Springs (NC); On-site; USD 140,000 - 200,000; Full time

Job summary

Amgen seeks a Principal Manufacturing Systems Engineer to join its advanced drug substance manufacturing plant in the U.S. You will lead the delivery of IS/Automation projects across a broad portfolio, ensuring alignment with corporate blueprints and business needs.

The role emphasizes collaboration with IS, manufacturing, and external partners to drive reliable, scalable systems. The position requires strong leadership, deep domain expertise in PCS/MES/Lab systems, and hands-on experience with

Qualifications

• Doctorate/ Master's/ Bachelor's/ Associate/ High school with extensive IS/Automation experience.
• Doctorate or Masters required with 2+ or 4+ years in IS, manufacturing automation.
• Experience in pharmaceutical/biotech manufacturing environments preferred.

Responsibilities

• Own delivery of IS/Automation projects with portfolio planning, resources, risk and financial management.
• Anticipate, evaluate and resolve multiple project issues using technical and business expertise.
• Translate strategic opportunities into executable plans aligned with standards and business needs.
• Elicit and analyze business needs and convert them to functional designs.
• Manage relationships with IS service owners, business partners, and vendors.

Skills

Lead cross-functional teams

Cyber security awareness

Problem solving

Effective communication

Education

Doctorate degree in Information Systems/Engineering

Master's degree in Information Systems/Engineering

Bachelor's degree in Information Systems/Engineering

Tools

Emerson DeltaV

Rockwell FactoryTalk

Rockwell PLCs

Aveva PI Data Historian

Kneat

Korber MES

GAMP lifecycle

21 CFR Part 11

Job description

Amgen seeks a Principal Manufacturing Systems Engineer to join its advanced drug substance manufacturing plant in the U.S. You will lead the delivery of IS/Automation projects across a broad portfolio, ensuring alignment with corporate blueprints and business needs.

The role emphasizes collaboration with IS, manufacturing, and external partners to drive reliable, scalable systems. The position requires strong leadership, deep domain expertise in PCS/MES/Lab systems, and hands-on experience with