Principal Manufacturing Associate

Immatics; Houston (TX); On-site; USD 100,000 - 150,000; Full time

Benefits offered by this job

Health insurance

4 weeks vacation plus prorated first/‑

12 holidays

Sick time 7 days

Life insurance 100% employer-paid

Disability coverage 100% employer-paid

401(k) with company match

Job summary

Immatics is seeking a Principal Manufacturing Associate to lead cell therapy manufacturing operations in a cGMP environment. Based on the Stafford, TX site, you will supervise staff, ensure adherence to cGMP, and drive continuous improvements in manufacturing processes.

You will coordinate with MSAT/PD, review batch records, and guide training while maintaining a safe, compliant work environment in a fast-paced setting. Strong leadership and manufacturing expertise are essential.

Qualifications

• 7+ years of cell therapy manufacturing or 4+ years with lead/supervisory experience.
• Degrees/certifications in biomanufacturing or related field as listed in Basic Qualifications.

Responsibilities

• Provide leadership, guidance, and training to staff in alignment with cGMP requirements.
• Instruct to facilitate workflow, shift activities, and shift exchanges ensuring tasks are completed.
• Maintain safe and controlled work environment and support deviation workflows.
• Review batch records and documents; coordinate with Training for manufacturing schedule.
• Collaborate with MSAT/PD to transfer projects into GMP; develop/update internal procedures.

Skills

cGMP compliance

leadership & training

shift coordination

batch records review

communication

team collaboration

problem solving

Education

Biomanufacturing AS Degree / Level 2 Certificate

Associate in Biology/Biochemistry/Biotechnology

Job description

Join Immatics and shape the future of cancer immunotherapy; one patient at a time!

Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME, a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T-cell therapies and TCR bispecifics.

Why Join Us?

• Innovative Environment: Help to pioneer advancements in cancer immunotherapy.
• Collaborative Culture: Be part of a diverse team dedicated to your professional growth.
• Global Impact: Contribute to therapies that make a lasting impact on patients globally.

We are seeking a Principal Manufacturing Associate to support our CMC-GMP team. This individual will provide direct leadership and oversight for the on-the-floor operations of cell therapy manufacturing in a cGMP environment.

Schedule

7:00am - 3:30pm; Monday to Friday; On-site

Reports to

Manufacturing Manager

Location

13203 Murphy Road Suite 100 Stafford, TX 77477

Basic Qualifications

• Biomanufacturing Technology Associate of Applied Science Degree, Biomanufacturing Technology Level 2 Certificate, or equivalent. or an Associate degree in Biology, Biochemistry, Biotechnology, Biomanufacturing or another related field.
• 7+ years of cell therapy manufacturing experience, or 4+ years of cell therapy manufacturing experience combined with lead or supervisory experience.

In This Role You Will

• Knowledge and adherence to cGMP requirements.
• Provide leadership, guidance, and necessary training to staff in alignment with cGMP requirements and established procedures
• Provide instruction to facilitate workflow, shift activities, and shift exchange ensuring all activities are completed as assigned.
• Provide a safe and controlled work environment.
• Provide deviation workflow support, including, but not limited to initiating, investigating, and troubleshooting deviations and unexpected events.
• Serve as backup for manufacturing associates for daily manufacturing processes.
• Review executed batch records and documents.
• Coordinate with the Training Department to include training needs on the manufacturing schedule.
• Clear communication with outgoing and incoming shift Leads and Managers to disseminate all relevant information.
• Collaborate with the MSAT/PD teams to transfer new projects into GMP.
• Develop or update internal policies, procedures or steps, identifies and elevate risks, communicates changes and plan for execution.
• Leads routine team meetings and huddles.
• Ability to work productively and to participate in a highly creative and fast-paced environment.

Work Environment

• cGMP clean room spaces and facilities (~80% of work hours).
• Grade A/B/C/D GMP environment with associated facility noise levels.
• While performing the duties of this job, you may routinely handle blood components and is occasionally exposed to temperatures between -196°C and 40°C, liquid nitrogen, liquid nitrogen vapor, dry ice, and carbon dioxide.
• Lifting: raising or lowering an object (up to 25 lbs.) from one level to another (includes upward pulling).
• Undergo and pass a color blindness evaluation and assessment of vision abilities required for this position.
• Must be able to push or pull carts and gas tanks on rolling wheels (approximately 50 lbs.).

What do we offer?

At Immatics, We Believe In Investing In Our Team’s Health, Safety And Well-being. Here’s What You Can Expect If You Join Immatics

Comprehensive Benefits

• Competitive rates for Health, Dental, and Vision Insurance
• 4 weeks of vacation granted up front each year and prorated for first and last year of employment.
• 12 company paid holidays
• 7 days of sick time
• 100% employer-paid life insuranceup to at 1x annual salary, up to one hundred thousand dollars
• 100% employer-paid short- and long-Term disability coverage
• 401(k) with immediate eligibilityand company match…
• The company will match 100% of your contributions up to 3% of your base salary for the first two years of employment, 4% for years 2-3 of employment, and up to 5% of your salary from the fourth year onward of continued employment.
• Partially paid parental leavefor eligible employees.
• Additional voluntary employee-paid benefits and services, including accident, hospital indemnity, and critical illness insurance, as well as identity theft protection and pet insurance.

Equal Employment Opportunity

We are an equal opportunity employer and are committed to building a diverse and inclusive workplace. We consider all qualified applicants for employment without regard torace, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexualorientation, gender identity or expression, national origin, ancestry, age, marital status, disability, geneticinformation, veteran status, or any other status protected by applicable law.

Reasonable Accommodations

We are committed to providing reasonable accommodations to individuals with disabilities and to applicants withsincerely heldreligious beliefs, practices, or observances. If you require assistance or accommodation during the application or interview process, please contact us [e-mail].

Work Authorization

Applicants mustbe authorized towork in the United States without the need for current or future sponsorship. Visa sponsorships may beavailablefor certain roles.

Pre-Employment Requirements

Employment is contingent upon successful completion of a background check, referencechecksand pre-employment drug screening, wherepermittedby applicable law. For certain roles, additionalscreenings such as a credit check or motor vehicle record review may be required, where job-related and consistent with business necessity.