Senior Manager, Accounting

Alnylam Pharmaceuticals; Cambridge (MA); Hybrid; USD 120,000 - 150,000; Full time

Job summary

A leading company in RNAi therapeutics is seeking a Senior Manager of Accounting to oversee core accounting functions, manage audits, and ensure compliance with U.S. GAAP and SOX. This hybrid role requires strong leadership skills and a deep understanding of financial regulations. The successful candidate will lead a team, drive process improvements, and support executive management with insights on complex transactions.

Qualifications

• Minimum 6 years relevant experience in public accounting or private industry.
• CPA license required.
• Deep knowledge of U.S. GAAP and SOX compliance.

Responsibilities

• Supervise and develop a team of 3 full-time employees.
• Oversee monthly, quarterly, and annual close processes for $1B+ of operating expenses.
• Act as the primary liaison with external and internal auditors.

Skills

Analytical Skills

Organizational Skills

Communication Skills

Problem Solving

Education

Bachelor’s degree in accounting

Master’s degree in accounting

Tools

SAP

Microsoft Excel

Job description

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Overview

We are seeking a highly skilled and strategic Accounting Senior Manager to supervise and scale Alnylam’s core accounting functions, including monthly close, audits, systems, and application of accounting policies. This role requires deep technical expertise in U.S. GAAP and Sarbanes-Oxley (SOX), and the ability to collaborate cross-functionally and solve complex problems across diverse subject areas.

This role is considered Hybrid and will be primarily located in Cambridge, MA.

Reporting and Responsibilities

• Supervise and develop a high-performing team of 3 full-time employees (1 direct report) and contractors based in Cambridge, MA, with potential team expansion.
• Oversee the monthly, quarterly, and annual close processes for $1B+ of operating expenses, including expense allocations and non-operating items in accordance with U.S. GAAP; identify opportunities for improvement to scale for growth.
• Manage foreign currency matters, including revaluation and translation adjustments.
• Oversee accounting for a $1B+ portfolio of debt securities.
• Collaborate with Facilities and Capital Projects teams on fixed assets and leases.
• Coordinate with FP&A, tax, and treasury to align actuals with forecasts and reconcile U.S. GAAP versus management reporting variances.
• Support external reporting, ensuring timely key inputs for SEC filings.
• Act as the primary liaison with external and internal auditors for smooth audit processes.
• Ensure effective internal controls over financial reporting in compliance with SOX.
• Identify and implement automation and process streamlining opportunities.
• Collaborate with technical accounting on complex transactions and support global process standardization.
• Provide insights and support to executive management, including on complex transactions.
• Drive staff development, mentorship, and succession planning.
• Lead ad hoc projects and analyses as assigned.

Qualifications

• Bachelor’s degree in accounting (Master’s preferred)
• Minimum 6 years relevant experience in public accounting or private industry
• CPA license required
• Deep knowledge of U.S. GAAP and SOX compliance
• Experience in global biotech preferred
• SAP experience strongly preferred

Competencies

• Strong analytical, organizational, and communication skills
• Detail-oriented with proactive problem-solving abilities
• Ability to work cross-functionally and independently
• Proficiency in Microsoft Excel and handling multiple priorities

About Alnylam

Alnylam Pharmaceuticals (Nasdaq: ALNY) pioneers RNA interference (RNAi) therapeutics, transforming lives with innovative medicines. Founded in 2002, we lead the RNAi Revolution, turning scientific possibility into reality.

Our Culture

We foster a people-first culture guided by core values: innovation, openness, urgency, excellence, and inclusivity. Recognized globally as a top employer, we are committed to diversity and equal opportunity.